Seeds in the appendix: a ‘fruitful’ exploration

Campora, Michela; Antonelli, Chiara Trambaiolo; Grillo, Federica; Bragoni, Alberto; Cornara, Laura; Migliora, Paola; Pigozzi, Simona; Mastracci, Luca

doi:10.1111/his.13211

Cited by 8 publications

(12 citation statements)

References 4 publications

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“…Many different types of seeds can be found in all gastrointestinal samples, as they often remain undigested due to the particular resistance of the seed's external cuticle to digestion. Various types of seeds have been reported in biopsy samples, polypectomy specimens and in various types of surgical specimens including appendicectomies, diverticular disease associated resections and cancers [59,60]. Among the most frequently found seeds, tomato seeds deserve more careful attention due to their complex morphology with glycoprotein-rich villi on the surface (which facilitate adhesion to the intestinal mucosa) making a misdiagnosis as parasites possible (Fig.…”

Section: Seedsmentioning

confidence: 99%

“Stranger things” in the gut: uncommon items in gastrointestinal specimens

et al. 2021

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Organic (such as parasites or vegetable remnants) and inorganic substances may be encountered during routine pathology diagnostic work up of endoscopic gastrointestinal biopsy samples and major resections, causing possible diagnostic conundrums for the young and not so young pathologists. The main aim of this review is the description of the most frequent oddities one can encounter as foreign bodies, in gastrointestinal pathology, on the basis of the current literature and personal experience. The types of encountered substances are divided into four principal categories: parasites (helminths such as Enterobius vermicularis, Strongyloides, Schistosoma, and Anisakis, and protozoa such as Entamoeba, Giardia and some intestinal coccidia); drugs and pharmaceutical fillers (found as deposits and as bystanders, innocent or not); seeds (possibly confused with worms) and plant remnants; pollutants (secondary to post-resection or post-biopsy contamination of the sample). An ample library of images is provided in order to consent easy referencing for diagnostic routine.

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Section: Seedsmentioning

confidence: 99%

“Stranger things” in the gut: uncommon items in gastrointestinal specimens

et al. 2021

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“…Starting from June 2017 to June 2020, all gastrointestinal pathology cases in which seeds or seed parts were found, were prospectively collected. The following data were registered: (1) patient related details such as gender and age, (2) sample site, (3) sample type (e.g., endoscopic biopsy, endoscopic polypectomy, surgical resection etc), (4) underlying disease, (5) seed type. Seed type was recognized by comparison with a reference image library of seeds and plant matter which have been formalin fixed, paraffin embedded, microtome cut (4-micron thick sections) and stained with Haematoxylin and Eosin (1,2).…”

Section: Methodsmentioning

confidence: 99%

“…The following data were registered: (1) patient related details such as gender and age, (2) sample site, (3) sample type (e.g., endoscopic biopsy, endoscopic polypectomy, surgical resection etc), (4) underlying disease, (5) seed type. Seed type was recognized by comparison with a reference image library of seeds and plant matter which have been formalin fixed, paraffin embedded, microtome cut (4-micron thick sections) and stained with Haematoxylin and Eosin (1,2). Up to now almost 70 different alimentary seeds have been categorized and photographed.…”

Section: Methodsmentioning

confidence: 99%

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The Seeds of Doubt: Finding Seeds in Intriguing Places

et al. 2021

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Introduction: Seeds may be found in gastrointestinal tissue samples, and their multifaceted appearance may be challenging. The aim is to report a rough incidence of pathology samples which show seeds, specify the most frequent sample types and show an iconography of the most commonly identified seeds.Materials and Methods: Between 2017 and 2020, all gastrointestinal pathology cases in which seeds/seed parts were found, were collected and seed type described by referencing a seed image library.Results: Fifty cases with complete seeds/seed parts were collected: 16 colonic resections for colorectal cancer and diverticulosis, 13 appendiceal resections for appendicitis, 1 gastric resection. Fifteen cases were found in polypectomy specimens and 5 cases in colorectal endoscopic biopsies. Most frequent seed types were tomato, kiwi, blueberry, and blackberry seeds.Conclusion: Seeds may be found in up to 4% of specimens; their recognition may be useful to exclude parasitic infections as well as in forensic sciences.

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“…We, therefore, decided to try to identify exactly what this thin, yellow object was and so contacted our botany colleague. We have previously had a rather fun time together, identifying seeds that often turn up in appendixes 1 and have managed to collect an extraordinary iconography of seed types.…”

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confidence: 99%