Sebaceous carcinoma of the parotid gland in children: An immunohistochemical and ploidy study

Altemani, Albina; Vargas, Pablo Agustı́n; Cardinali, I.; Aguiar, Simone S.; Lopes, Márcio Ajudarte; Soares, Andresa Borges; Speight, Paul M.; Almeida, Orlando José de

doi:10.1016/j.ijom.2008.02.007

Cited by 11 publications

(18 citation statements)

References 29 publications

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“…The parotid gland is the most common of the noncutaneous sites of SBC due to the increased number of ectopic sebaceous glands in parotid in comparison to other salivary glands. We have found more extraocular cases (55.1%) than periorbital tumors in the present series because the orbital tumors are operated and diagnosed in a separate ophthalmic centre at our institute.…”

Section: Discussionmentioning

confidence: 66%

Cytomorphology of sebaceous carcinoma with analysis of p40 antibody expression

Jain

Mathur

Sharma

et al. 2015

Diagnostic Cytopathology

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Section: Discussionmentioning

confidence: 66%

Cytomorphology of sebaceous carcinoma with analysis of p40 antibody expression

Jain

Mathur

Sharma

et al. 2015

Diagnostic Cytopathology

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“…Considering the salivary glands, most cases involve the parotid gland and are rarely reported in the other major glands or intraorally [ 1 , 2 , 3 , 4 ]. In the English literature, only 24 cases of sebaceous carcinoma (SC) in the parotid gland have been reported [ 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 ]. SC in the parotid gland has a bimodal age distribution, with a peak in the second decade and another one in the seventh decade of life (with a range of 6–92 years).…”

Section: Introductionmentioning

confidence: 99%

“…This is also the age distribution of sebaceous cells which appear in the normal salivary gland and the adjacent regions. They are rarely seen in children under the age of 10 years [ 6 ] but appear to increase in numbers in the second decade of life. It has been suggested that this may reflect the same hormonal stimulus that activates the sebaceous glands in the skin during puberty.…”

Section: Introductionmentioning

confidence: 99%

Sebaceous Carcinoma of the Parotid Gland: A Case Report

Takada¹,

Kawamoto²,

Baba³

et al. 2015

Case Rep Oncol

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Background: Primary sebaceous carcinoma of the parotid gland is extremely rare, and because of its rarity, clinicopathological characteristics and histogenesis are not fully understood. Methods: Here, we report a patient who presented with a left infra-auricular painless mass. We present the histological features and discuss possible optimal treatments based on previous literature. Results: The mass was suspected to be a myoepithelial tumor or possibly a pleomorphic adenoma. Initially, the mass was resected with preservation of the facial nerve, but this caused facial palsy. Because the histological examination showed a sebaceous carcinoma and a part of the mass could be remaining on the facial nerve, additional surgery was performed, and the facial nerve was reconstructed with cervical nerve. Follow-up after 7 months showed no sign of recurrence of metastasis. Conclusion: We encountered a rare sebaceous carcinoma of the parotid gland. Additional surgery was performed because preoperative diagnosis was difficult.

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“…Sebaceous carcinoma is a rare neoplasm with aggressive growth. Most frequently, this tumor presents in the cutaneous tissues of the periocular region, typically on the eyelid, but it has also been described less commonly in other locations, including as a primary tumor of the parotid gland . It usually presents as a painless, round nodule, and clinically mimics benign or less aggressive lesions .…”

mentioning

confidence: 99%

“…Sebaceous glands have been reported in the parotid gland of 28% of autopsy specimens and 24% of surgical specimens, but both benign and malignant sebaceous salivary gland tumors are extremely rare, making up less than 0.2% of all major salivary glands neoplasms. Given the rarity of primary sebaceous carcinomas in salivary glands, the prognosis of this tumor is unknown, especially as a range of biologic behavior has been described in extraocular tumors . Additionally, it is difficult to distinguish a primary sebaceous carcinoma of the salivary gland from a metastasis from an occult primary skin lesion .…”

mentioning

confidence: 99%