Seasonal variation in phenolic composition and antioxidant and anti-inflammatory activities of Calamintha nepeta (L.) Savi

The relevance of pharmacognosy in pharmacological research on herbal medicinal products

“…Not only the content of polyphenolic constituents but also the in vitro bioactivity of the respective extracts was found to be subject to seasonal variaton in Thymus longicaulis C. Presl. and Calamintha nepeta (L.) Savi [65,66]. Fig.…”

Spatial and Temporal Variations in Secondary Metabolites Content of the Brazilian Arnica Leaves (Lychnophora ericoides Mart., Asteraceae)

“…[8][9][10] As a strategy to adapt and survive under damaging conditions, plants use many complex biochemical processes to create chemical defense mechanisms, and this behavior cannot be neglected in pharmacology of medicinal plants. Thus, there are many phytochemical studies evaluating seasonal effects in the bioactive secondary metabolite production, [11][12][13] and relating their importance to the environment, 8 to understand the behavior of these plants.…”

“…[8][9][10] As a strategy to adapt and survive under damaging conditions, plants use many complex biochemical processes to create chemical defense mechanisms, and this behavior cannot be neglected in pharmacology of medicinal plants. Thus, there are many phytochemical studies evaluating seasonal effects in the bioactive secondary metabolite production, [11][12][13] and relating their importance to the environment, 8 to understand the behavior of these plants.The genus Lychnophora (from Asteraceae family) is a plant endemic in Brazil, that has been used as a prospective source of natural products.14 This plant usually grows in the Cerrado, where are found only few arboreous and herbaceous species. 15 Some species of Lychnophora are extensively used in traditional Brazilian herbal medicine as anti-inflammatory, as well as analgesic, antimicrobial and anti-rheumatism agent.…”

Influence of harvest time on the phenolic content of horseradish leaves

“…(Capanoglu, 2010). A group of researchers found that content of phenolic acids (for example caffeic acid) of areal parts of Calamintha nepeta L. Savi was significantly higher at the flowering stage than at the post flowering stage (Pacifico et al, 2015).There is no general tendency for differences of TPC in horseradish roots depending on genotype and harvest time (Tomsone et al, 2012).…”

“…Several authors have reported that antioxidant activity (AA) and chemical composition are influenced by the harvest time, as well as the content of compounds and properties vary from plant development stages (Imene et al, 2012;Tomsone et al, 2012;Marrelli et al, 2012). The content and composition of phenolic compounds and antioxidant potential of areal parts of Calamintha nepeta L. Savi (Lamiaceae) was significantly affected by ontogenic growth stages (Pacifico et al, 2015). Tunisian researchers have found that for some plants (O. ficus-indica (L.) Mill.…”