The relevance of pharmacognosy in pharmacological research on herbal medicinal products

Pferschy‐Wenzig, Eva‐Maria; Bauer, Rudolf

doi:10.1016/j.yebeh.2015.05.037

Cited by 90 publications

(77 citation statements)

References 178 publications

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“…3 It is well accepted that plants possess multitude of phytochemicals because of inherent inconsistency and a plethora of environmental factors. 4 Thus, a well defined and constant composition of the drug is therefore one of the most important criteria for the execution of its quality. Moreover, pharmacognostic study is the preliminary step in the standardization of the crude drugs in order to ensure safety and consistency.…”

Section: Introductionmentioning

confidence: 99%

Quality Control standardization of Wild Himalayan Pear: Pyrus pashia

Hemalatha¹,

Sharma²,

Prasad³

2016

Phcogj

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Introduction: To establish the pharmacognostical and phytochemical standardization parameters of Pyrus pashia fruits in order to ensure quality and safety of this traditionally acclaimed medicinal tree. Methods: The fresh fruits of P. pashia were collected and dried. Fruit was subjected to various pharmacognostical investigations, Extraction procedures, and preliminary phytochemical screening, according to WHO guidelines. Ethanolic extract was standardized to total phenolic and flavonoid content, followed by phyto chemical quantification of P. pashia extract using lupeol as a chemical marker by HPLC method. Results: In the present study, microscopy of the fruit showed typical characteristics of berry, having thick fleshy pericarp differentiated into thin epicarp and thick mesocarp having wide radiating carpel chambers with one or two seeds attached in axile placentum. Further, physicochemical evaluation was done like, loss on drying, total ash value, acid insoluble ash value, water soluble ash value, fluorescence analysis etc. Heavy metal and pesticide residue analysis was also performed. Furthermore, ethanolic extract of Pyrus pashia (EPP) obtained from cold maceration and phytochemical screening of different fractions obtained by

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Section: Introductionmentioning

confidence: 99%

Quality Control standardization of Wild Himalayan Pear: Pyrus pashia

Hemalatha¹,

Sharma²,

Prasad³

2016

Phcogj

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“…In the present short communication, a new and rapid Headspace Solvent Micro Extraction (HSME) method is utilized, for the extraction and preconcentration of the volatile and anti-cancer compounds such as N-Tolyl-Sulfonyl-Phosphoramid-Saeure-Dichlorid from plant samples into a microdrop [1][2][3][4][5][6][7][8][9]. The extraction occurred by suspending a microdrop of the solvent from the tip of a micro syringe to the headspace of the dried and powdered plants samples in a sealed vial for a preset extraction time [10][11][12][13][14][15].…”

Section: Editorialmentioning

confidence: 99%

Extraction and Preconcentration of N-Tolyl-Sulfonyl-Phosphoramid- Saeure-Dichlorid as an Anti-Cancer Drug from Plants: A Pharmacognosy Study

Heidari¹

2016

J Pharmacogn Nat Prod

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“…Different phytoconstituents are the primary source in the pharmaceutical industry for the development of new drugs from the 19 th century which was the time of rational drug discovery. [1,2] The World Health Organization (WHO) defines the herbal medicines as the materials and preparations which are derived from plants having a beneficial effect on human's health [3] and serve a valuable role in traditional systems of medicine worldwide. It is estimated that 70% people of the world depend on these herbal medicines to fulfill their basic health needs, [4,5] possibly due to local availability, high potency, cost-effectiveness, and safer drug profile of those preparations and plants.…”

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confidence: 99%

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Reddy

2017

IJGP

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Background and Aim of Study: The main aim of this research is to establish a standardized data regarding its safety through including certain parameters. Kadali (Musa paradisiaca) Linn. (Musaceae) is a perennial herb which is like a tree and is used in Ayurvedic system of medicine to cure many diseases. Materials and Methods: In the present study, pharmacognostical and phytochemical standardization of plant material was performed as per the guidelines of World Health Organization. Results: The stamen of M. paradisiaca is brownish black or dull in color, slightly smooth and 0.9-1.6 cm long depending on the maturity of stamen. Powdered microscopy of stamen of M. paradisiaca shows some fiber vascular tissues, prism-like calcium oxalate crystal, pigmented sclereids, and spherical pollen grains. Physicochemical parameters including loss on drying (5.5% w/w), total ash (5.81%), water-soluble ash (3.79% w/w), acid-insoluble ash (2.61% w/w), water-soluble extractive (7.17% w/w), methanol-soluble extractive (2.38% w/w), hexane-soluble extractive (1.44% w/w), ethyl acetate-soluble extractive (2.24% w/w), and petroleum ether-soluble extractive (4.0% w/w) were evaluated. Phytochemical screening of aqueous and methanolic extracts showed the presence of alkaloids, carbohydrates, saponins, tannins, and phenols. Safety and efficacy of plant drug was further performed through evaluating heavy metals (Zn, Cd, and Pb). Heavy metals are discovered within the permissible limits. Conclusion: The diagnostic characters of stamen will give the necessary information regarding its identification. Its physiochemical and phytochemical evaluation provides information which accounts for the safety, identification, and class of chemical constituents present in this crude drug.

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The relevance of pharmacognosy in pharmacological research on herbal medicinal products

Cited by 90 publications

References 178 publications

Quality Control standardization of Wild Himalayan Pear: Pyrus pashia

Quality Control standardization of Wild Himalayan Pear: Pyrus pashia

Extraction and Preconcentration of N-Tolyl-Sulfonyl-Phosphoramid- Saeure-Dichlorid as an Anti-Cancer Drug from Plants: A Pharmacognosy Study

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