Seasonal variation for the antidiabetic activity of Loranthus micranthus methanol extract

Osadebe, PO; Omeje, Edwin Ogechukwu; Uzor, Philip F.; Ernest, David; Obiorah, Damian Chiedozie

doi:10.1016/s1995-7645(10)60008-9

Cited by 38 publications

(31 citation statements)

References 7 publications

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“…Interestingly, Tannins, saponins, glycosides, and reducing sugars were not found in July samples. However, higher amounts of flavonoids and oils were detected in July samples compared to April ones [29]. Iwalokun and colleagues [30] have investigated the phytochemicals such as n -butanol, chloroform, ethyl acetate, and water fractions of the methanolic extract of L. micranthus leaves of Kola nut tree ( K. acuminata ).…”

Section: Phytochemistrymentioning

confidence: 99%

“…The low-acidic fraction at the dose of 400 mg/kg reduced 66.60% of blood sugar level of alloxan-induced diabetic rats at 24 hours after administration [28]. However, Osadebe and colleagues [29] have studied the seasonal variation for the anti-diabetic effect of the aqueous methanolic extract of the leaves of L. micranthus, parasitic on P. americana, in alloxan-induced diabetic rats. The study demonstrated that anti-diabetic effect of the extract is seasonal and dose dependent with the highest activity being at the peak of the rainy season.…”

Section: Biological Activitiesmentioning

confidence: 99%

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Loranthus micranthusLinn.: Biological Activities and Phytochemistry

Moghadamtousi

Hajrezaei

Kadir

et al. 2013

Evidence-Based Complementary and Alternative Medicine

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Loranthus micranthus Linn. is a medicinal plant from the Loranthaceae family commonly known as an eastern Nigeria species of the African mistletoe and is widely used in folkloric medicine to cure various ailments and diseases. It is semiparasitic plant because of growing on various host trees and shrubs and absorbing mineral nutrition and water from respective host. Hence, the phytochemicals and biological activities of L. micranthus demonstrated strong host and harvesting period dependency. The leaves have been proved to possess immunomodulatory, antidiabetic, antimicrobial, antihypertensive, antioxidant, antidiarrhoeal, and hypolipidemic activities. This review summarizes the information and findings concerning the current knowledge on the biological activities, pharmacological properties, toxicity, and chemical constituents of Loranthus micranthus.

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Section: Phytochemistrymentioning

confidence: 99%

Section: Biological Activitiesmentioning

confidence: 99%

Loranthus micranthusLinn.: Biological Activities and Phytochemistry

Moghadamtousi

Hajrezaei

Kadir

et al. 2013

Evidence-Based Complementary and Alternative Medicine

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“…This confirmation justifies its use in ethnomedical medicine for the treatment of diabetes [29][30] .…”

Section: Discussionmentioning

confidence: 58%

Antidiabetic and hypolipidemic activities of ethanolic leaf extract and fractions of Melanthera scandens

Akpan

Okokon

Offong

2012

Asian Pacific Journal of Tropical Biomedicine

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“…In other species the season was important to increase the bioactivity, for example, the antidiabetic activity of Loranthus micranthus was highest at the peak of the rainy season. [40] The influence of season on phytochemical profile and thus bioactivity might be attributed to environments conditions as well as different phenology stages. Without isolating a single factor, it is impossible to link the increase in secondary metabolite production to factor unique, as the other factors have also proven to affect secondary metabolism.…”

Section: Seasonality and Foliar Phenologymentioning

confidence: 99%

Spatio‐Temporal Variation of Alkaloids in Annona purpurea and the Associated Influence on Their Antifungal Activity

De-la-Cruz-Chacón

Riley‐Saldaña

Arrollo‐Gómez

et al. 2019

Chemistry & Biodiversity

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Annona purpurea grows in the areas of low elevation in deciduous forests of Mexico, those areas have marked rainy and dry seasons. This species produces more than 30 bioactive alkaloids that could have potential in the control of phytopathogens. This research provides data on the variation of the content and number of alkaloids during an annual cycle and the associated inhibitory potential of the compounds against three phytopathogenic fungi. For one year, alkaloidal extracts of stems and leaves were obtained every two months. The extract profiles were determined by gas chromatography with tandem mass spectrometry and their antifungal activity was examined in vitro. The alkaloids, annomontine and oxopurpureine, obtained from the roots and leaves, respectively, were also evaluated individually. The yields, profiles and activities of the extracts, as well as the abundance of annomontine and oxopurpureine in the extracts, were contrasted with the seasonality and phenological phases of the plant. The data indicate that the alkaloid content was higher at the height of the dry season. High yields also occurred during flowering. The strongest inhibitory effect was obtained from the root extracts during the last month of dry season. This finding seems to be explained by the higher chemodiversity of alkaloids in extracts from this season. Annomontine and oxopurpureine inhibited all three phytopathogens; however, they were not solely responsible for the activity of A. purpurea.

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Seasonal variation for the antidiabetic activity of Loranthus micranthus methanol extract

Cited by 38 publications

References 7 publications

Loranthus micranthusLinn.: Biological Activities and Phytochemistry

Loranthus micranthusLinn.: Biological Activities and Phytochemistry

Antidiabetic and hypolipidemic activities of ethanolic leaf extract and fractions of Melanthera scandens

Spatio‐Temporal Variation of Alkaloids in Annona purpurea and the Associated Influence on Their Antifungal Activity

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