“…In vivo and in vitro studies have shown that 2,4-dihydroxybenzophenone (BP-1), 2,2 0 ,4,4 0 -tetrahydroxybenzophenone (BP-2), 2-hydroxyl-4-methoxyl benzophenone (BP-3) and 2-hydroxyl-4-methoxyl benzophenone-5-sulfonic acid (BP-4) exhibit estrogenic and anti-androgenic activities (Kunz et al, 2006). Thus, occurrence (Liao and Kannan, 2014;Tsui et al, 2014;Tsai et al, 2014), degradation (Beel et al, 2013;Duirk et al, 2013;Ji et al, 2013;Laurentiis et al, 2013;Xiao et al, 2013;Yang and Ying, 2013) and, particularly, the potential toxicities to humans and ecosystems of these compounds have attracted widespread attention (Hofkamp et al, 2008;Downs et al, 2014;Paredes et al, 2014). Recently, BP-3 was found in nearly all urine samples from the U.S. and China .…”