Hepatic oxidative stress biomarker responses in freshwater fish Carassius auratus exposed to four benzophenone UV filters

Non-targeted metabolomics reveals alterations in liver and plasma of gilt-head bream exposed to oxybenzone

“…The alterations of metabolites in lipid metabolism can be related to oxidative stress since several authors have reported that UV filters such as oxybenzone generate oxidative stress in fish (Liu et al, 2015;Rodríguez-Fuentes et al, 2015). Similarly to the present work, lipid storage disorder associated with oxidative stress has been already reported as an adverse effect of different xenobiotics (Buron et al, 2017;Salihovic et al, 2016;Wafa et al, 2011).…”

“…For instance, a growing trend in glutathione peroxidase expression was observed in zebrafish (Danio rerio) eleuthero-embryos exposed to oxybenzone, which is an indicative of oxidative stress (Rodríguez-Fuentes et al, 2015). In the same context, Liu and co-workers also reported that benzophenone UV filters generated oxidative stress in freshwater fish Carassius auratus (Liu et al, 2015).…”

“…Consequently, occurrence of UV filters in aquatic ecosystems and their potential effects on non-target organisms is of growing concern (Blüthgen et al, 2012;Coronado et al, 2008;Díaz-Cruz and Barceló, 2009;Fent et al, 2010;Ghazipura et al, 2017;Kinnberg et al, 2015;Kunz et al, 2006;Liu et al, 2015;Rodríguez-Fuentes et al, 2015;Tsui et al, 2014). For instance, developmental and reproductive toxicity of oxybenzone (Coronado et al, 2008;Ghazipura et al, 2017;Kinnberg et al, 2015) in fish have been attributed to an altered hormonal balance as a result of its endocrine disrupting effects (Ghazipura et al, 2017;Kinnberg et al, 2015).…”

“…xenobiotics show up to three distinct modes of action, including estrogenicity, antiestrogenicity and anti-androgenicity (Blüthgen et al, 2012;Kinnberg et al, 2015;Kunz et al, 2006). Additionally, the scarce information available regarding their effects on the antioxidant defense system in fish suggests that UV filters have adverse effects beyond hormonal activity (Liu et al, 2015;Rodríguez-Fuentes et al, 2015). For instance, a growing trend in glutathione peroxidase expression was observed in zebrafish (Danio rerio) eleuthero-embryos exposed to oxybenzone, which is an indicative of oxidative stress (Rodríguez-Fuentes et al, 2015).…”

CoMn2O4 Catalyst Prepared Using the Sol-Gel Method for the Activation of Peroxymonosulfate and Degradation of UV Filter 2-Phenylbenzimidazole-5-sulfonic Acid (PBSA)

“…Given their dramatically increasing daily use, UV filters are continuously being discharged into the aquatic environment, and have become a class of emerging contaminants (ECs) and also formed “false persistent” pollution [1,2]. A large number of studies have shown that some organic UV filters can mimic the effects of various hormones in living organisms, thereby interfering with the normal endocrine functions of animals and humans, resulting in potentially serious health threats [3,4,5,6,7,8]. Unfortunately, UV filters are relatively stable in nature and are considered difficult to be biodegraded, making it difficult for municipal wastewater treatment plants to completely remove them during treatment [9,10].…”