2001
DOI: 10.1007/s004170100319
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Scleral buckling versus primary vitrectomy in rhegmatogenous retinal detachment (SPR Study): Design issues and implications

Abstract: The SPR Study is the first randomised prospective clinical trial to compare scleral buckling and primary vitrectomy in patients with RRD. The results of this study should enable vitreoretinal surgeons to improve the surgical therapy of patients with the more complicated manifestations of RRD.

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Cited by 101 publications
(104 citation statements)
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“…Although this undertaking has been reported to lower the redetachment rate due to new breaks, 20 investigators are not of one mind as to the benefits it confers. 16,21 However, although not statistically significant, the anatomical success rates after primary scleral buckling plus vitrectomy in phakic and pseudophakic eyes were lower than after scleral buckling alone. This may relate to the circumstance that vitrectomy was reserved for complicated cases of RD.…”
Section: Discussionmentioning
confidence: 92%
“…Although this undertaking has been reported to lower the redetachment rate due to new breaks, 20 investigators are not of one mind as to the benefits it confers. 16,21 However, although not statistically significant, the anatomical success rates after primary scleral buckling plus vitrectomy in phakic and pseudophakic eyes were lower than after scleral buckling alone. This may relate to the circumstance that vitrectomy was reserved for complicated cases of RD.…”
Section: Discussionmentioning
confidence: 92%
“…This includes the number of breaks, the extent of the retinal detachment, the presence of PVR before surgery, the involvement of the macular region, the height of the retinal detachment (bullous or not), refractive errors , the lens status and others. The effect of these factors on the functional and anatomic outcome of retinal detachment surgery has been previously investigated in the ‘Scleral Buckling versus Primary Vitrectomy in Rhegmatogenous Retinal Detachment (SPR)’ trials [9,10,11], which were designed to compare SB surgery and primary pars plana vitrectomy in rhegmatogenous retinal detachments of medium complexity. The categories of severity described in our study are based on the inclusion and exclusion criteria of the SPR trail [11].…”
Section: Discussionmentioning
confidence: 99%
“…This causes a separation of the neuroretina from the retinal pigment epithelium. 1 If untreated, most RRD will progress to a complete detachment and subsequently result in vision loss of the affected eye. 1 The annual incidence of RRD is about 10 per 100 000 persons.…”
Section: Introductionmentioning
confidence: 99%
“…1 If untreated, most RRD will progress to a complete detachment and subsequently result in vision loss of the affected eye. 1 The annual incidence of RRD is about 10 per 100 000 persons. 2,3 The following predictors were found to be risk factors for functional and anatomic success after primary RRD repair: more than 6 days of visual loss, 4 macular involvement and the size of detachment area.…”
Section: Introductionmentioning
confidence: 99%