Schwannoma of the hard palate

Lollar, Kevin W.; Pollak, Natasha; Liess, Benjamin D.; Miick, Ronald; Zitsch, Robert P.

doi:10.1016/j.amjoto.2008.11.009

Cited by 40 publications

(43 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Il faut savoir que le risque de dégénérescence et de récidive du schwannome est très rare voire exceptionnel, cela s'explique par l'encapsulation du schwannome [10][11][12][13]. À l'inverse, le neurofibrome n'est pas une tumeur encapsulée et un taux de récidive d'environ 23,5 % est observé pour les neurofibromes solitaires.…”

Section: Discussionunclassified

Neurofibromatose, frontière entre schwannome et neurofibrome. À propos d’un cas clinique et revue de littérature

Bernardo

Butel

Langlois

et al. 2015

Med Buccale Chir Buccale

View full text Add to dashboard Cite

Résumé -Introduction :Aujourd'hui, les pathologistes s'accordent à dire que schwannome, neurinome, neurilemmome et fibroblastome périneural sont des synonymes, ils font partie des neurofibromatoses de type II. Observation : Il s'agissait d'une patiente initialement adressée pour un schwannome bénin intramandibulaire. Cette lésion présentait des ressemblances sur le plan clinique et radiologique avec le schwannome, mais cette piste diagnostique n'était pas confirmée par le médecin anatomo-pathologiste. Discussion : Les anatomo-pathologistes distinguent cette tumeur du neurofibrome, retrouvé dans la neurofibromatose de type I. En effet, les neurofibromes prennent naissance à partir d'éléments conjonctifs (cellules de Schwann, fibroblastes et autres cellules du périnèvre) alors que les schwannomes sont une prolifération à partir de cellules de Schwann uniquement. Le diagnostic en est d'autant plus difficile et dépend de la pièce opératoire à analyser ainsi que de la compétence de l'anatomo-pathologiste. Conclusion : Cette observation clinique illustre la difficulté de la démarche diagnostique quand le clinicien fait face à des tumeurs peu fréquentes. Elle conforte la place de l'examen anatomo-pathologique dans la quête du diagnostic positif.Abstract -Neurofibromatosis, frontier between schwannoma and neurofibroma. A case report and literature review. Introduction: Today, pathologists agree that schwannoma, neurinoma, neurilemmoma and perineural fibroblastoma are synonymous; they are part of neurofibromatosis type II. Observation: A female patient presented mandibulary lesions initially diagnosed as a schwannoma. Indeed, the clinical and radiological aspects of these lesions showed similarities to schwannoma. However, this initial clinical diagnosis was not confirmed by the pathologist. Discussion: Pathologists differentiate schwannoma from neurofibroma, found in neurofibromatosis type I. Indeed, neurofibroma is formed by conjunctive elements (Schwann cells, fibroblasts and other cells of the perineurium), whereas schwannoma is exclusively a proliferation of Schwann cells. So, the diagnosis will be harder, and depends on the surgical specimen to be analysed and the ability of the pathologist. Conclusion: This clinical case illustrates the challenge of delivering a pertinent diagnosis and, finally, it highlights the importance of the histological examination for a positive diagnosis.

show abstract

Section: Discussionunclassified

Neurofibromatose, frontière entre schwannome et neurofibrome. À propos d’un cas clinique et revue de littérature

Bernardo

Butel

Langlois

et al. 2015

Med Buccale Chir Buccale

View full text Add to dashboard Cite

show abstract

“…Schwann cells are neural crestderived glial cells that are responsible for providing myelin insulation to peripheral nervous system axons. In the head and neck, two notable exceptions of nerves lacking Schwann cell encasement are the optic and olfactory nerve [22]. Schwannomas were first described by Verocay in 1908 [3,6].…”

Section: Discussionmentioning

confidence: 99%

“…4 The mass was well encapsulated, measuring 2 cm in diameter usually asymptomatic. Depending on the location of the tumor and its mass effect or nerve involvement, patients may report symptoms such as pain, hoarseness, dysphagia, cranial nerve neuropathies, and even Horner syndrome [22,23].…”

Section: Discussionmentioning

confidence: 99%

“…Extracranially, about 25% of all schwannomas are located in the head and neck, but only 1% shows an intraoral origin [21]. The most common intraoral sites are the tongue, followed by the palate, the floor of the mouth, the buccal mucosa, the gingiva, the lips, and the vestibular mucosa [9,22]. The cyst may arise at any age, the peak incidence is between third and sixth decades.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Schwannoma of Tongue

Moreno-García

Pons-García

González-García

et al. 2011

J. Maxillofac. Oral Surg.

View full text Add to dashboard Cite

show abstract

“…2 About a quarter of all schwannomas occur in the head and neck region. Only 1% of these occur intraorally, generally in the tongue.…”

Section: Introductionmentioning

confidence: 99%

Schwannoma in oropharynx: a rare site posing diagnostic challenge

2017

View full text Add to dashboard Cite

Schwannomas are benign nerve sheath tumors. These arise from Schwann cells of the neural sheath. Intra oral region is a relatively uncommon site of these tumors. They are solitary, slow growing, smooth surfaced, usually asymptomatic, and encapsulated tumors, about 25% of all schwannomas are located in the head and neck, but only 1% show intraoral origin. A 22-year-old female came with dysphagia since, 3 years. FNAC was not feasible and so excision biopsy of the lesion was performed. Histopathology revealed schwannoma like picture and it was confirmed with diffuse S-100 positivity on immunohistochemistry. Hence, finally confirming schwannoma of the oropharyngeal region. Schwannomas can be found anywhere in the body but a quarter of all occur in the head and neck region. Intraorally its percentage is only 1% with tongue being the commonest. Pharyngeal presentations of schwannoma are rare. Schwannomas are benign tumors having excellent prognosis. Basically, this case report is important as these very rarely occur in the oropharyngeal region and it’s a must to consider them in the differential diagnosis of lesions at this site.

show abstract

Schwannoma of the hard palate

Cited by 40 publications

References 5 publications

Neurofibromatose, frontière entre schwannome et neurofibrome. À propos d’un cas clinique et revue de littérature

Neurofibromatose, frontière entre schwannome et neurofibrome. À propos d’un cas clinique et revue de littérature

Schwannoma of Tongue

Schwannoma in oropharynx: a rare site posing diagnostic challenge

Contact Info

Product

Resources

About