Schwannoma of Tongue

Moreno-García, Carlos; Pons-García, María Asunción; González-García, Raúl; Monje-Gil, Florencio

doi:10.1007/s12663-010-0101-0

Cited by 36 publications

(47 citation statements)

References 18 publications

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“…Complete surgical excision is the treatment of choice. Schwannoma rarely recurs, but when it does, it is usually due to incomplete excision 10. In the presented case the outcome was good with complete functional and aesthetic restoration.…”

Section: Discussionmentioning

confidence: 64%

“…Occurrence of all schwannomas in the head and neck is 25–45% and of these 1–12% can be found intraorally 9. In the oral cavity the tongue is most frequently affected, followed by the roof of the mouth, the floor of the mouth, the buccal mucosa, the gingiva, the lips and the vestibular mucosa 10. In the tongue, identification of the originating nerve (hypoglossal, glossopharyngeal and lingual) is difficult given their proximity.…”

Section: Introductionmentioning

confidence: 99%

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Schwannoma of the tongue

Kavčič

Božić²

2016

BMJ Case Reports

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Schwannoma, neurilemmoma or neurinoma is a rare, benign nerve sheath neoplasm composed of Schwann cells. It is usually solitary, slow growing and asymptomatic. Approximately 1-12% of the tumours occur intraorally with the tongue being the most common location. We report a rare case of lingual schwannoma in a 20-year-old female patient involving the tip of the tongue, which was slow growing and asymptomatic. For diagnosis histopathological examination and also immunohistochemistry testing were carried out to confirm the nature of tissue fragments. The treatment was complete surgical excision.

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Section: Discussionmentioning

confidence: 64%

Section: Introductionmentioning

confidence: 99%

Schwannoma of the tongue

Kavčič

Božić²

2016

BMJ Case Reports

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“…1 Schwann cells form a thin barrier around each extracranial nerve fiber of motor and sensory nerves and wrap larger fibers with myelin sheath to enhance nerve conductance. 9,10 The possible etiologies of the tongue schwannoma are spontaneous growth, external injury, chronic irritation, or exposure to radiation; but the certain cause of the tongue schwannoma is unknown. 7,11 Loss of function of the merlin protein (coded by gene NF2) appears to be the cause of the appearance of schwannomas.…”

Section: Discussionmentioning

confidence: 99%

“…13,14,22,23 The differential diagnosis must be made relative to malignant tumours based on the speed of growth and clinical appearance, includes squamous cell carcinoma and angiosarcoma. 1,2,10,15,18 When the lesion presents as an exophytic mass, the possibility of a papilloma, aberrant thyroid tissue, and hypertrophied lingual tonsil tissue must also be included. 22 Histologically, the differential diagnosis includes all spindle cell lesions at base of tongue including sarcamatoid squamous cell carcinoma, smooth muscle, fibroblastic, lipomatous, and rarely salivary gland tumours.…”

Section: Discussionmentioning

confidence: 99%

Base of tongue schwannoma on a 22 year old lady: a rare case

Indrasari

Fedriani

2017

Int J Otorhinolaryngol Head Neck Surg

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Schwannomas are benign tumours arising from the Schwann cells. Around 25-45% schwannomas have been reported occured in head and neck region, but only 1% located intraoral. We report a case of 22 year old woman who presented with foreign body sensation in throat, dysphagia, change of voice, and snoring. There was a slowly growing, solitary, encapsulated, painless, mass on the tongue base. Microscopically, it had the typical features of schwannoma, the diagnosis being supported by a strong positivity for S-100 protein. Ki67 staining showed low proliferative index (<5%) indicated benign schwannoma. CT-scan of oropharynx demonstrated a well-circumscribed soft tissue density mass, oval shape, connected with the left portion base of tongue, homogenous, and strong enhancement mass. The entire mass was removed in general anesthesia with conservative surgical excision via trans-oral route, histopathologic reported consistent as schwannoma. The patient remained disease-free, without any residual problems. Although the rarity of schwannoma on the tongue base, this case highlights the importance of including it in the differential diagnosis of mass from the tongue base. To the best of our knowledge, our case is only the twentieth of schwannoma at the base of tongue that reported in the literature. <p> </p>

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“…Macroscopic presentation of lesion following surgical excision. 16,21 Histologically Schwannomas are usually encapsulated and shows proliferation of spindle shaped-shaped cells, which assume two different patterns. The hypercellular areas, so-called Antoni type A, consists of spindle shaped cells organised in a palisaded pattern usually around eosinophilic areas, forming the so-called Verocay bodies.…”

Section: Acronymsmentioning

confidence: 99%