Schiff base metal complexes: Synthesis, characterization, thermal analysis and antibacterial activity

Paul, Tuly; Hossen, Faruk; Kudrat-E-Zahan,; Haque, M. Shamsul; Hossain, Saddam; Zamir, Rausan; Asraf, Ali

doi:10.5958/0974-4150.2020.00052.8

Cited by 2 publications

(1 citation statement)

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“…The antibacterial potential of metal complexes when combined with Schiff base is enhanced against Bacillus cereus and E. coli . This enhanced activity of the complexes may be attributed to chelation of Schiff base with metal ions that provide stability and more susceptibility against the bacterial pathogens [ 113 ]. Similarly, Schiff base (4-chloro-2-{(E)-[(4-fluorophenyl) imino] methyl} phenol) when reacting with metal (II) complexes (Mn (II), Co (II), Ni (II), Cu (II), and Zn (II)) show antibacterial activity against both Gram-positive bacteria such as Bacillus subtilis and Staphylococcus typhi and Gram-negative bacteria such as Escherichia coli and Pseudomonas aeruginosa [ 114 ].…”

Section: Pharmaceutical Uses Of Metal and Its Complexesmentioning

confidence: 99%

Antimicrobial Agents Based on Metal Complexes: Present Situation and Future Prospects

Sharma

Shukla²,

Rattan

et al. 2022

International Journal of Biomaterials

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The rise in antimicrobial resistance is a cause of serious concern since the ages. Therefore, a dire need to explore new antimicrobial entities that can combat against the increasing threat of antibiotic resistance is realized. Studies have shown that the activity of the strongest antibiotics has reduced drastically against many microbes such as microfungi and bacteria (Gram-positive and Gram-negative). A ray of hope, however, was witnessed in early 1940s with the development of new drug discovery and use of metal complexes as antibiotics. Many new metal-based drugs were developed from the metal complexes which are potentially active against a number of ailments such as cancer, malaria, and neurodegenerative diseases. Therefore, this review is an attempt to describe the present scenario and future development of metal complexes as antibiotics against wide array of microbes.

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Section: Pharmaceutical Uses Of Metal and Its Complexesmentioning

confidence: 99%