Scedosporium apiospermum, an emerging pathogen in India: Case series and review of literature

Rynga, Dabet; Capoor, Malini R.; Varshney, Swati; Naik, Mayuresh; Gupta, Vijay

doi:10.4103/ijpm.ijpm_742_16

Cited by 9 publications

(4 citation statements)

References 2 publications

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“…Till date five cases of rhinosinusitis caused by Scedosporium species are reported in English literature[Table 1]. [45678] In present case, the patient is a known diabetic on oral hypoglycemic drugs with adequate blood sugar control who is doing well on 6 months follow up.…”

Section: Discussionmentioning

confidence: 94%

Scedosporium apiospermum as a rare cause of fungal rhinosinusitis

Baidya

Gupta

Basu

et al. 2019

J Family Med Prim Care

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Section: Discussionmentioning

confidence: 94%

Scedosporium apiospermum as a rare cause of fungal rhinosinusitis

Baidya

Gupta

Basu

et al. 2019

J Family Med Prim Care

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“…An erroneous assumption of Aspergillus infection could result in the administration of inappropriate/ineffective antifungal therapy and worse clinical outcome. There is only one other report in the literature of Scedosporium apiopermum infection in an immunocompetent patient [5].…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Fungal Rhinosinusitis Caused by Scedosporium apiopermum

Naik

Bhatt

Richards

et al. 2020

Head and Neck Pathol

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Fungal rhinosinusitis (FRS) is inflammation of the paranasal sinus mucosa due to fungal infections, which can be invasive or non-invasive. The occurrence of a sphenoid mucocele with a fungal ball is rare. We report a case of sphenoid sinus mucocele with a fungal ball caused by Scedosporium apiopermum in a 32-year-old female who presented to the Emergency Department with persistent headache not relieved on medications. The radiological images showed a mucocele with clival osteomyelitis. Urgent endoscopic examination and debridement was undertaken which demonstrated a mucocele with fungal ball. Microbiological examination confirmed it to be Scedosporium apiopermum.

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“…The eye is rarely involved, but such keratomycosis is usually caused by plant-related injuries [ 5 ]. Although keratitis caused by SA is rare, several cases have been reported [ 6 , 7 ]. Early diagnosis is of the utmost importance, since the immediate initiation of antifungal therapy may improve the final prognosis, along with anatomical and functional recovery [ 8 ].…”

Section: Introductionmentioning

confidence: 99%

Scedosporium apiospermum contact lens-related keratitis: A rare case report and a literature review

Cassano¹,

Cardascia²,

Tegola³

et al. 2021

Med Hypothesis Discov Innov Ophthalmol

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Background: Scedosporium apiospermum (SA) is commonly present in temperate climates. It can induce cutaneous and subcutaneous tissue infections as well as disseminated infections in immunocompromised or immunocompetent hosts. The eye is rarely involved. Keratomycosis is usually caused by plant-related injuries. Here, we describe a patient with a severe and sight-threatening corneal abscess caused by SA, which was associated with contact lens wear and was successfully treated with a combination of surgical and medical therapies. Case Presentation: An otherwise healthy 22-year-old woman, with history of contact lens wearing, was referred to the Ophthalmic Department of Bari University, Bari, Italy for evaluation of a corneal abscess and hypopyon in her left eye. Intensive topical and systemic antibiotic therapy was initiated after obtaining conjunctival swabs. Within 2 days, her ophthalmic condition had worsened, and her best-corrected visual acuity (BCVA) dropped to counting fingers. She underwent penetrating keratoplasty, after which her ophthalmic condition improved. Microbiological culture, obtained from the explanted cornea, revealed SA infection. This was addressed with specific topical and systemic therapy using voriconazole. Two weeks later, the condition of her left eye was stable, with mild corneal edema and no sign of acute graft rejection. Her BCVA improved to 20/25, and all medications were discontinued, except for the steroid eye drop. The patient was scheduled for a 1-month follow-up. Conclusions: Prompt identification of the etiological agent is mandatory to perform appropriate therapy in cases of keratomycosis. Surgery to remove the infected cornea is helpful in patients with deteriorating condition, in whom the initial medical therapy has failed. Topical and systemic antimycotic therapy, based on microbiological culture, is recommended as an adjunctive therapy for the surgical management of severe corneal mycotic abscesses. How to cite this article: Cassano F, Cardascia N, Tegola MGL, Boscia F, Alessio G. Scedosporium apiospermum contact lens-related keratitis: A rare case report and a literature review. Med Hypothesis Discov Innov Ophthalmol. 2021 Summer, 10(2): 80-85 https://doi.org/10.51329/mehdiophthal1425

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Scedosporium apiospermum, an emerging pathogen in India: Case series and review of literature

Cited by 9 publications

References 2 publications

Scedosporium apiospermum as a rare cause of fungal rhinosinusitis

Scedosporium apiospermum as a rare cause of fungal rhinosinusitis

A Rare Case of Fungal Rhinosinusitis Caused by Scedosporium apiopermum

Scedosporium apiospermum contact lens-related keratitis: A rare case report and a literature review

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