Scalp immersion proxigraphy (SIP): an improved imaging technique for phototrichogram analysis*

Neste, D.J.J. Van; Dumortier, M.; Brouwer, Bernadette de; Coster, W. De

doi:10.1111/j.1468-3083.1992.tb00631.x

Cited by 27 publications

(14 citation statements)

References 6 publications

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“…The salient feature of the immersion photo graphy study was a better evaluation of LHGR as compared to PT data [5], Measurements with the classic PT underestimated this vari able by approximately 30% compared with micrometric values (0.27 vs. 0.37 mm/day, re spectively). This high distortion by PT, we believe, was due to a two-dimensional projec tion of the three-dimensional image (parallax error).…”

Section: Discussionmentioning

confidence: 99%

The Phototrichogram: Analysis of Some Technical Factors of Variation

Dj¹,

B²,

W³

1994

Skin Pharmacol Physiol

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Photographic methods for hair evaluation are frequently proposed as an alternative to more invasive methods (trichogram or biopsy). The reliability in terms of quantitative follow-up of hair growth has not been evaluated properly. We report results of comparative studies of scalp hair evaluation with various photographic methods. Statistically significant findings were a better detection of scalp hairs using the original enlargement × 3 as compared to × 2 (212 vs. 167 hair follicles/cm²) and a more acceptable estimate of linear hair growth rate with ‘scalp immersion proxigraphy’ (SIP) (0.317 mm/day) as compared with classical phototrichogram pictures where this variable was underestimated by 30% on average (0.27 mm/day). SIP-generated linear hair growth rates were very close to the micrometric method (0.37 mm/day). Therefore SIP × 3 images appear preferable for hair growth monitoring during clinical trials.

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Section: Discussionmentioning

confidence: 99%

The Phototrichogram: Analysis of Some Technical Factors of Variation

Dj¹,

B²,

W³

1994

Skin Pharmacol Physiol

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“…A similar approach has been tested with the use of the phototrichogram, which has proven to be a suitable and noninvasive tool to monitor the hair growth phases in situ. This technique has been improved by the image analysis [9] and later with the use of immersion oil and digital contrast enhancement [10]. However, although a marked improvement of the images and more accurate quantitative data were collected, a fully automated analysis is not yet possible to our knowledge as this technique still relies on processing by qualified technicians and computer-assisted image analysis.…”

Section: Discussionmentioning

confidence: 99%

Trichoscan: What Is New?

Hoffmann

2005

Dermatology

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The treatment of androgenetic alopecia (AGA) is usually long lasting, and the effects of treatment attempts are difficult to measure. Consequently, there was a need for a sensitive tool to monitor hair loss and treatment response. Therefore, we developed the Trichoscan as a method which combines epiluminescence microscopy with automatic digital image analysis for the measurement of human hair. The Trichoscan is able to analyze all important parameters of hair growth (density, diameter, growth rate, vellus and terminal hair density) with an intraclass correlation of approximately 91% within the same Trichoscan operator and an intraclass correlation of approximately 97% for different Trichoscan operators. The application of the technique was demonstrated by comparison of the hair parameters in 9 men with frontal balding which were treated for 6 months with 5% minoxidil. Even in this small cohort of patients, we noticed after 3 months of treatment compared to baseline a significant increase in hair density (+21.3 hairs/cm²; p = 0.047) and cumulative hair thickness (+0.61 mm; p = 0.008) and after 6 months a significant increase in hair density (+34 hairs/cm²; p = 0.011) and cumulative hair thickness (+0.88 mm; p = 0.010). The study shows that the Trichoscan has many advantages. It can be used for clinical studies to compare placebo versus treatment or to compare the relative potencies of different hair-growth-promoting substances. It can be used for studying AGA or other forms of diffuse hair loss, and it can be adopted to study the effect of drugs or laser treatment on hypertrichosis or hirsutism. The drawbacks, however, are that the Trichoscan still needs a hair dye for contrast enhancement and the measurement area must be clipped before analysis. This mini-review summarizes recent attempts to optimize the technique and shows new options such as the calculation of follicular units or the ‘anagen hair count’.

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“…They are mistakenly considered as missing. The contrast-enhanced phototrichogram is designed to help to distinguish hair on a skin background of the same colour [103][104][105][106]. Application of dyes on hair is quite convenient for such a purpose.…”

Section: Phototrichogram and Videotrichogrammentioning

confidence: 99%

EEMCO Guidance for the Assessment of Hair Shedding and Alopecia

Pierard

Piérard-Franchimont

Marks

et al. 2004

Skin Pharmacol Physiol

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Knowledge of the hair follicle anatomy and the dynamics of hair cycling is substantial. Recognizing the anagen, catagen and telogen phases as well as teloptosis and the hair eclipse phenomenon clearly characterizes the typical hair chronobiology. Physiological modulators include hormones, neuromediators, miscellaneous biomolecules, seasons, micro-inflammation and ageing. For individuals who present with the complaint of increased hair shedding or alopecia, a host of evaluation techniques are available in addition to history, physical examination and laboratory assessment. Various clinical hair techniques can help in assessing the efficacy of drugs and cosmetics on hair growth. The methods are quite similar to those used to establish a definite diagnosis in dermatological practice. Great strides have been made during the recent decades in the methodology of hair growth trials in dermatology and cosmetology. Clinical evaluations benefit from a few additional specific techniques that enhance the perception of hair (re-) growth, shedding and alopecia. These assessments include the determination of hair patterning and density that may be helped by the ‘black-and-white felt’ examination. Daily hair counts, the ‘hair pull test’ and the ‘hair feathering test’ are also available. Instrumental methods provide reliable quantitative information that is useful if there are adequate controls. Some photographic methods, the trichogram, hair weighing and variants of the hair growth window technique including the phototrichogram, videotrichogram and tractio-phototrichogram provide insight into the complexities of hair cycling and shedding. Skin biopsy is indicated for diagnostic purposes, especially when the hair loss is accompanied by scarring.

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Scalp immersion proxigraphy (SIP): an improved imaging technique for phototrichogram analysis*

Cited by 27 publications

References 6 publications

The Phototrichogram: Analysis of Some Technical Factors of Variation

The Phototrichogram: Analysis of Some Technical Factors of Variation

Trichoscan: What Is New?

EEMCO Guidance for the Assessment of Hair Shedding and Alopecia

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