SALMONELLA MENINGITIS<subtitle>Recovery from Meningitis Due to Salmonella Sp. (Type Montevideo), with Consideration of the Problem of Salmonella Meningitis</subtitle>

Salmonella Meningitis: Report of Three Cases in Adults and Literature Review

“…In a review of data from the New York Salmonella Center from 1939-1955 by Saphra and Winter [9], only 74 of 9,518 isolates were from the CSF and several extensive reviews of bacterial meningitis reported no cases of Salmonella infection [10,11]. Almost all reported cases have occurred in children, especially infants [1,6,12,13]. In two series of patients with typhoid fever, Osler [14] reported 11 of 2,000 patients with meningitis and Osuntokun [15] noted confusional states in 57% of 959 cases, although meningitis occurred in only 0.2% of cases.…”

“…19 patients were treated with sulfadiazine, of whom 52% recovered, while of those untreated only 6% recovered. Beene et al's review in 1951 [12] reported a 83% mortality for patients treated with chloramphenicol and tetracycline. In the 1960's and 1970's mortality declined to 59-62% in developing countries [1,15] and 30-37% in America and Europe [22,27], as more effective diagnostic and therapeutic agents became available.…”

Typhoid fever in African and Indian children in Durban.

“…Meningitis due to an organism of the genus salmonella is said to be four times as frequent in children as in adults (Beene, Hansen, and Fulton, 1951). The earliest review on the subject of typhoid meningitis was that of Cole (1904) in which he collected 13 proved cases.…”

Salmonella Meningitis in Infancy

“…Only 10 cases were found in the English literature f which were not included in the last comprehensive survey, in 1951. 2 The six cases that were found at this hospital occurred over a 10-year period, during which time approximately 330 cases of purulent meningitis were diagnosed bacteriologically. This makes the incidence of Salmonella menin¬ gitis here 1 to every 55 cases of meningitis.…”