1987
DOI: 10.1164/ajrccm/136.2.305
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Salivary Cotinine Levels and Involuntary Tobacco Smoke Exposure in Children and Adults in New Mexico

Abstract: We conducted a population-based household survey of respiratory disease in 2,029 children and adults and measured salivary cotinine levels by radioimmunoassay in 1,360 nonsmokers and ex-smokers. At all ages median and mean cotinine levels among nonsmokers and ex-smokers increased with the number of smokers in the home. The prevalence of a detectable level of cotinine was about 35% for those not living with a cigarette smoker and was greater with the number of cigarettes smoked by household members. In a multip… Show more

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Cited by 70 publications
(44 citation statements)
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“…Smoking at home explains almost 40% of the variability of the CCR and similar observations have been made in many earlier studies with preschool or school children (Jarvis et al, 1985(Jarvis et al, , 1987Coultas et al, 1987;Forastiere et al, 1993;Cook et al, 1994;Dell'Orco et al, 1995;Bono et al, 1996;Jordaan et al, 1999;Scherer et al, 1999). In a study carried out in Scotland, the number of smokers in the household Exposure of children to ETS Scherer et al accounted for as much as 51% of the observed variance in saliva cotinine (Jarvis et al, 1992).…”
Section: Etssupporting
confidence: 64%
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“…Smoking at home explains almost 40% of the variability of the CCR and similar observations have been made in many earlier studies with preschool or school children (Jarvis et al, 1985(Jarvis et al, , 1987Coultas et al, 1987;Forastiere et al, 1993;Cook et al, 1994;Dell'Orco et al, 1995;Bono et al, 1996;Jordaan et al, 1999;Scherer et al, 1999). In a study carried out in Scotland, the number of smokers in the household Exposure of children to ETS Scherer et al accounted for as much as 51% of the observed variance in saliva cotinine (Jarvis et al, 1992).…”
Section: Etssupporting
confidence: 64%
“…In our population, the effect of paternal smoking is only observable when the mother is a nonsmoker. In other studies, a somewhat larger effect of fathers' smoking was reported (Jarvis et al, 1985;Coultas et al, 1987;Jordaan et al, 1999). Our observation that children whose mother smoked during pregnancy and children who reportedly were ETS exposed during the first 3 years of life exhibit significantly higher urinary cotinine levels in the univariate analysis reflects the fact that mothers who smoke during these periods are more likely to be persistent and heavy smokers, as can be seen in the comparison between Tables 2 and 4, demonstrating that the effect of these variables vanished after adjusting for actual smoking behaviour.…”
Section: Etsmentioning
confidence: 75%
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“…In that study, the hair nicotine level in the children ages 2 to 5 years was approximately six times higher than in older children, ages 9 to 14 years, at the same levels of parental smoking. In addition, Coultas et al (37) found that the median of saliva cotinine concentrations among nonsmoking children ages <5 years was about twice higher, compared with that among older children ages 6 to 12 years when there was one cigarette smoker in the home. Coultas et al (37) also reported that presence and the concentration of saliva cotinine were affected by all household smokers at home.…”
Section: Determinants For Hair Nicotine Concentrations Among Women Anmentioning
confidence: 99%
“…32 An alternative would be to measure urine or saliva cotinine, a metabolite of nicotine, in infants and children. 28,35 Not only are urine and saliva cotinine important biomarkers for ETS exposure, they may serve as motivation and intervention tools to promote healthy environments. However, the pediatrician should bear in mind that cotinine is a short-term marker of exposure that is easily affected by the level of exposure and metabolic rate.…”
Section: Reducing Ets Exposure Health Effects Of Ets On Childrenmentioning
confidence: 99%