The Griffon Vulture (Gyps fulvus) vulture is a large species with a vast range spanning from the Iberian Peninsula in the west to the Himalaya in the east. Kazakhstan lies on the north-easternmost edge of the species’ distribution range and according to literary data, in the 20th century it was considered a common species in Kazakhstan. However, there is no recent robust estimation of species abundance and distribution and in recent times researchers found that Griffon Vulture was in the past often mistaken for the Himalayan Vulture, resulting in the need to question everything known about the species in Kazakhstan. Hence, the aim of the current study was to review published data on the Eurasian Griffon vulture in Kazakhstan as a first step. As a second step, we aimed to validate field data by visiting colonies and establishing species status and abundance in Kazakhstan. The only large breeding population with several colonies of the species in the country is in the Karatau mountains where we focused our efforts. Cases of Griffon Vulture found nesting in other regions are rare or absent. We counted the number of occupied nests in two different years – 2010 and 2022 — and we registered a 95% decrease in the number of active nests. In 2010, 74 active nests were found opposed to only 4 found in 2022. The reasons for the rapid decline in the number of Griffon Vulture are poorly understood. Official data from the Kazakhstan government authorities confirms that non-steroidal anti-inflammatory drugs (NSAIDs) containing diclofenac, ketoprofen, and flunixin are used in the country. Meanwhile, despite the critical drop in numbers, the Griffon Vulture is still not a protected species in Kazakhstan. We recommend urgent measures to understand the scale of the reported threats and the implementation of conservation actions.