S1262 High-Resolution Colonic Manometry: Have We Been Incorrectly Labeling Colonic Motor Patterns?

Neuroanatomy and physiology of colorectal function and defaecation: from basic science to human clinical studies

“…For this application, the process refers to the distortion or artefact that may result when a signal is sampled at sensor spacing greater than that of the propulsive activity itself. A recent pilot study utilizing a high‐resolution fibreoptic manometry catheter (32 sensors at 1 cm intervals) indicates that this may indeed be the case 37 . Analysis of the complete dataset and then subsampling different sets of the full array to simulate different sensor spacing indicated that not only do investigators miss short extent propagating sequences (PS) there is also a risk of identifying false PS as well as mislabeling the polarity (i.e.…”

The Physiology of Human Defecation

“…As a caveat, it should be noted however, that the majority of colonic manometries have been performed with recording sites spaced 10 cm or more apart. A recent study using high resolution manometry with 1 cm sensor spacing indicates that manometric pressure patterns often propagate for less than 10 cm [144], which indicates propagated activity may have been previously ''mislabeled'' as non-propagated [141]. Although the role of non-propagated activity in luminal transport is not fully understood [141], it is thought to aid mixing of intraluminal contents by local propulsion [145,146] and retropulsion [147] of the fecal bolus.…”

High -resolution imaging of esophageal pressure waves based on fiber gratings

“…Indeed, the number of sensors can be increased, which offers the promise of novel uses, for example, colonoscopic measurements, 12 where good spatial resolution prevents artifacts in diagnostics. 13 As next steps, we plan to improve the cross-sensitivity of the sensors (e.g., to temperature) and to take into account increased functionalities, such as acidity detection.…”