S117 Effects of Intensive Cell Phone (Philips Genic 900) Use on the Rat Kidney Tissue

Koca, Orhan; Gökçe, Ali Murat; Öztürk, Metin İshak; Ercan, Feríha; Yurdakul, Necati; Karaman, Muhammet İhsan

doi:10.1016/s1569-9056(13)60309-7

Cited by 14 publications

(14 citation statements)

References 19 publications

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“…The qualitative and quantitative changes investigated in this study suggest that EMF increases the free radical activity in cells (Grundler et al, 1992) and disturbs the ROS metabolism by increasing the production of ROS or by decreasing the activity of antioxidant enzymes (Al-Damegh, 2012). Therefore, RF-EMF exposure led to an increase in the levels of oxygen radicals in kidney and liver tissues in our study and these observations are supported by several studies (Devrim et al, 2008;Oktem et al 2005;Özgüner et al, 2005;Koca et al, 2013;Koyu et al, 2005). However, Ozguner et al (2005) reported similar changes in testicular tissue, but not in kidney or liver tissue.…”

Section: Discussionsupporting

confidence: 90%

Microwave radiation (2.45 GHz)-induced oxidative stress: Whole-body exposure effect on histopathology of Wistar rats

Chauhan

Verma

Sisodia

et al. 2016

Electromagnetic Biology and Medicine

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Man-made microwave and radiofrequency (RF) radiation technologies have been steadily increasing with the growing demand of electronic appliances such as microwave oven and cell phones. These appliances affect biological systems by increasing free radicals, thus leading to oxidative damage. The aim of this study was to explore the effect of 2.45 GHz microwave radiation on histology and the level of lipid peroxide (LPO) in Wistar rats. Sixty-day-old male Wistar rats with 180 ± 10 g body weight were used for this study. Animals were divided into two groups: sham exposed (control) and microwave exposed. These animals were exposed for 2 h a day for 35 d to 2.45 GHz microwave radiation (power density, 0.2 mW/cm). The whole-body specific absorption rate (SAR) was estimated to be 0.14 W/kg. After completion of the exposure period, rats were sacrificed, and brain, liver, kidney, testis and spleen were stored/preserved for determination of LPO and histological parameters. Significantly high level of LPO was observed in the liver (p < 0.001), brain (p < 0.004) and spleen (p < 0.006) in samples from rats exposed to microwave radiation. Also histological changes were observed in the brain, liver, testis, kidney and spleen after whole-body microwave exposure, compared to the control group. Based on the results obtained in this study, we conclude that exposure to microwave radiation 2 h a day for 35 d can potentially cause histopathology and oxidative changes in Wistar rats. These results indicate possible implications of such exposure on human health.

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Section: Discussionsupporting

confidence: 90%

Microwave radiation (2.45 GHz)-induced oxidative stress: Whole-body exposure effect on histopathology of Wistar rats

Chauhan

Verma

Sisodia

et al. 2016

Electromagnetic Biology and Medicine

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“…12 In previous studies, it was reported that EMR produced from mobile phones may affect the immune, nervous, hematological and urinary systems as well as the cardiac functions, genetics and the normal growth and development of humans. [12][13][14] In their study, Ono et al 15 could not determine any significant difference in DNA mutation between the non-exposed group and the embryos exposed to EMR for 16 hours daily for 15 days. However, EMR produced from mobile phones appears to have harmful effects on the human body in two different ways.…”

Section: Discussionmentioning

confidence: 81%

“…Koca et al 13 investigated the harmful effects of EMR radiating from mobile phones on rat kidneys by both light and electron microscopies. Light microscope findings included damage in the glomerulus, dilatation in Bowman's capsule, large gaps between tubules that were damaged, perivascular edema and inflammatory cell infiltration.…”

Section: Discussionmentioning

confidence: 99%

The effect of exposure of rats during prenatal period to radiation spreading from mobile phones on renal development

et al. 2014

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Background: The aim of this study was to investigate the effects of exposure to a 900-MHz electromagnetic field (EMF) produced by mobile phones on the renal development of prenatal rats. Histopathological changes and apoptosis in the kidneys, together with levels of urea, creatinine and electrolyte in serum were determined. Methods: A total of 14 Sprague-Dawley rats were studied. Pregnant rats were divided into two equal groups: a control group and an EMF-exposed group. The study group was exposed to 900-MHz of EMF during the first 20 days of pregnancy, while the control group was unexposed to EMF. Sections obtained from paraffin blocks were stained for caspase-3 by immunohistochemistry, hematoxylin-eosin and Masson's trichrome. Results: Mild congestion and tubular defects, and dilatation of Bowman's capsule were observed in the kidney tissues of rats in the exposed group. Apoptosis was evaluated using anti-caspase-3; stronger positive staining was observed in the renal tubular cells in the study group than those of the control group. Although there was a significant difference between the study and control groups in terms of K + level (p50.05), no significant difference was observed in the other parameters studied (p40.05). Conclusion: Our study shows that the electromagnetic waves propagated from mobile phones have harmful effects on the renal development of prenatal rats.

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“…In previous studies urinary bladder [12] and kidney damages [19] were observed on mature rats after exposing EMW for 20 days. In an another study EMW exposure was applied to the rats in prenatal period and observed harmful effect on the kidney development [20].…”

Section: Discussionmentioning

confidence: 94%

The morphological and biochemical investigation of prenatal electromagnetic wave effects on urinary bladder in rats

Kiran¹,

Tok²,

Şehirli³

et al. 2017

Marmara Medical Journal

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The morphological and biochemical investigation of electromagnetic wave effects on urinary bladder in prenatal ratsPrenatal sıçan mesanesi üzerine elektromanyetik dalganın etkilerinin morfolojik ve biyokimyasal olarak incelenmesi ÖZ Amaçlar: Bu çalışmanın amacı, dijital mobil telefonlarından gelen ve en yüksek spesifik absorbsiyon oranı (Specific Absorbtion Rate-SAR) değeri 1,79W/kg olan dijital selüler sistem (DSS) 1800-MHz radyasyonunun erkek sıçan mesanesi üzerine etkilerini araştırmaktır.Gereç ve Yöntem: Sıçanlara mobil telefondan stand-by (Stand-by Fetal grup) ya da kesintisiz iletim modunda yayılan elektromagnetik dalga (EMD Fetal grup), günde 2 saat, embriyonik 14. günden doğuma kadar ya da doğumdan sonraki 60. güne kadar (Stand-by ve EMD grupları) uygulanmıştır. Deney gruplarındaki tüm hayvanların mesaneleri postnatal 60. günde eter anestezisi altında alınmış ve ışık ve elektron mikroskopik değerlendirmeler için hazırlanmıştır. Ürotelyumun bariyer fonkisyonu zonula okludens 1 ve E-kaderin immunhistokimyası ve transmisyon elektron mikroskobik inceleme için rutenyum kırmızısı boyaması ile değerlendirilmiştir. Oksidatif hasar biyokimyasal teknikler ile değerlendirilmiştir.Bulgular: Elektromagnetik dalga grubunda, ürotelyum dökülmeleri, mast hücre sayısında artış, sıkı bağlantılarda hasar ve interselüler alanda genişlemeler gözlenmiştir. Son olarak, kontrol grubu ile kıyaslandığında, tüm gruplarda malondialdehit seviyesinde yükselme ve glutatyon seviyesinde düşüş gözlenmiştir.Sonuç: Elektromagnetik dalga, maruz kalınan yoğunluk ve süreye paralel olarak, gelişim sürecindeki mesane üzerine olumsuz etki yapmaktadır. Bu değişiklikler mesanede enflamatuvar hastalıklara sebep olabilir.

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S117 Effects of Intensive Cell Phone (Philips Genic 900) Use on the Rat Kidney Tissue

Cited by 14 publications

References 19 publications

Microwave radiation (2.45 GHz)-induced oxidative stress: Whole-body exposure effect on histopathology of Wistar rats

Microwave radiation (2.45 GHz)-induced oxidative stress: Whole-body exposure effect on histopathology of Wistar rats

The effect of exposure of rats during prenatal period to radiation spreading from mobile phones on renal development

The morphological and biochemical investigation of prenatal electromagnetic wave effects on urinary bladder in rats

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