Romifidine as a constant rate infusion in isoflurane anaesthetized horses: a clinical study

Effects of a constant rate infusion of detomidine on cardiovascular function, isoflurane requirements and recovery quality in horses

“…In contrast with the results of Kuhn et al. (2004), a CRI of the same α 2 ‐agonist (romifidine 40 μg kg −1 hour −1 ) did not affect cardiovascular function (including CI), isoflurane requirement or recovery quality in isoflurane anaesthetized horses undergoing elective surgery (Devisscher et al. 2010).…”

Evaluation of the clinical efficacy of two partial intravenous anesthetic protocols, compared with isoflurane alone, to maintain general anesthesia in horses

“…35 Indeed, the analgesic and sedative efficacy of romifidine 24,36,37 could have contributed to both the hemodynamic stability and better recoveries. 40 In equine patients, maintenance of adequate cardiovascular variables is extremely important because decreased peripheral perfusion can lead to myopathies caused by reduced muscular blood flow. McMurphy et al 12 observed that horses receiving TIVA had higher blood pressures than did those in which anesthesia was maintained with halothane.…”

Is there a place for dexmedetomidine in equine anaesthesia and analgesia? A systematic review (2005–2017)

“…This is of extreme importance in horses with infusions of α 2 ‐agonists, in which a “lighter” appearance, compared with traditional inhalant protocols, is common (Kalchofner et al., ). No isoflurane concentration reductions were demonstrated after romifidine (Devisscher, Schauvliege, Dewulf, & Gasthuys, ), detomidine (Schauvliege et al., ) and dexmedetomidine (Marcilla et al., ). The same happened in the comparison between medetomidine and dexmedetomidine (Sacks et al., ).…”