Role of ultrastructural studies in the analysis of cell lineage in the mammalian pre‐implantation embryo

Abstract

Ultrastructural studies have contributed significantly to our understanding of cell lineage differentiation in the mammalian pre-implantation embryo. Such studies have documented, and continue to document, morphological, biochemical, and physiological characteristics of the cell lineages established during the pre-implantation period in eutherian embryos, principally that of the mouse. This review evaluates these contributions and identifies areas of study in which ultrastructural analysis is most likely to have an important role in the future.

High Resolution Scanning Electron Microscopy of Cells Using Dielectrophoresis

“…Pharmacological endeavors of drug discovery and investigating drug effects have also utilized ultrastructural cell analysis [16]–[18]. Furthermore, in fundamental biology, characterization of important biological structures such as presynaptic terminals, and examination of embryonic cell lineage differentiation has also been enabled [19], [20].…”