Role of Tsukamurella species in human infections: first literature review

Abstract

Tsukamurella is an aerobic, Gram-positive and nonmotile bacterium. It was first isolated in 1941 from the mycetoma and ovaries of the bedbug. The primary strains were named Corynebacterium paurometabolum and Gordona aurantiaca and are different from the Collins et al., 1988 classification of the new Tsukamurella genus. Human infections with Tsukamurella species are rare because the species is a kind of saprophyte bacterium; however, most information regarding this species comes from case reports. Molecular markers for the identification Tsukamurella include sequencing of 16S rRNA, groEL, rpoB, secA1 and ssrA genes. Given the lack of information on the treatment of Tsukamurella infections, a combination of various antibiotic agents is recommended.

Pyrosequencing Uncovers a Shift in Bacterial Communities Across Life Stages of Octodonta nipae (Coleoptera: Chrysomelidae)

“…Also, Pantoea from grasshopper possesses antagonistic activity and inhibit the growth and spore formation of fungi Metarhizium anisopliae ( Dillon and Charnley, 1995 ). Bacterium Tsukamurella is a human opportunistic pathogen ( Safaei et al, 2018 ), however, its function is largely unknown in insects.…”

Commensal and Pathogenic Members of the Dental Calculus Microbiome of Badia Pozzeveri Individuals from the 11th to 19th Centuries

“…The presence of opportunistic pathogens associated with cystic fibrosis, such as Burkholderia gladioli and Inquilinus limosus [37,38], respiratory tract infection bacteria such as Tsukamurella pulmonis [39], potential nosocomial pathogens including Methylobacterium mesophilicum [40], Microbacterium oxydans , which was isolated from human throat swabs [41], bacteria isolated from peritoneal carcinomatosis, intra-abdominal infections, and scleromas including Lentzea albidocapillata , Necropsobacter rosorum , and Arthrobacter scleromae , respectively [42,43,44], is intriguing and could suggest that these subjects could have been affected by respiratory illnesses and other opportunistic pathogens. However, data should be carefully interpreted due to limitations of sequencing one 16S rRNA gene variable region for species-level resolution.…”

Williamsia spp. are emerging opportunistic bacteria

“…Adsorption of acetate, 2,3-butandiol, citrate, mannitol, paraffin, sorbitol, trehalose, adonitol, adipate, isoamyl alcohol, l -arabinose, cellobiose, meso-erythritol, m-hydroxybenzoate, p-hydroxybenzoate, myo-inositol, lactate, melezitose, 1,2-propandiol and carbohydrates as carbon sources are usually labor intensive and time consuming. Further, many reports of Williamsia infection are usually misdiagnosed as Rhodococcus and other actinomycete infections; thus, analyzing whole fatty-acid cell walls via molecular methods (such as DNA hybridization techniques and 16S rRNA gene sequencing) is a rapid, accurate and reliable method for identifying actinomycete infections, especially Williamsia infection [2] , [4] , [5] , [8] .…”