Objective: To evaluate the quantity of prenatal care as a risk factor for giving birth to low birth weight (LBW), preterm, and small for gestational age (SGA) infants in a sample of women diagnosed with depressive disorder.
Method:Our study used a population-based dataset, Taiwan's National Health Insurance Research Database, which we linked to Taiwan's birth certificate registry to identify a total of 5283 new mothers with depressive disorder. Multivariate logistic regression analyses were performed to measure the risk of giving birth to LBW, preterm, and SGA infants, relating to the number of prenatal care visits (10 or more, 8 to 9, and 7 or less) made by mothers with depressive disorder.Results: After adjusting for a woman's age, monthly income, urbanization level of place of residence, geographic location, marital status, substance abuse, arterial hypertension, diabetes, anemia, coronary heart disease, malpresentation, insufficient or excessive fetal growth, placenta or previa abruption, and infant's sex and parity, regression analyses revealed that mothers with a history of depressive disorder who received prenatal care 7 times or less were 4.21 (95% CI 3.34 to 5.32, P < 0.001), 5.37 (95% CI 4.33 to 6.67, P < 0.001), and 2.41 (95% CI 2.03 to 2.86, P < 0.001) times as likely to have LBW, preterm, and SGA babies, respectively, compared with mothers with depressive disorder who received prenatal care visits 10 times or more.
Conclusions:Mothers with a history of depressive disorder who make fewer prenatal care visits were at an increased risk of LBW, SGA, and preterm birth, compared with women with a history of depressive disorder who made an adequate number of prenatal visits.Can J Psychiatry. 2011;56(5):273-280.
Clinical Implications• Mothers with a history of depressive disorder who received 7 or less prenatal care visits had significantly higher percentages of LBW (20.0% compared with 5.2% compared with 8.7%), preterm (25.8% compared with 5.7% compared with 11.4%), and SGA (32.8% compared with 16.5% compared with 21.1%) births compared with women who received 10 or more and 8 to 9 prenatal care visits, respectively.• Mothers with a history of depressive disorder who received prenatal care 7 times or less were 4.21, 5.37, and 2.41 times as likely to have LBW, preterm, and SGA babies, respectively, compared with mothers with a history of depressive disorder who received prenatal care 10 times or more.
Limitations• Administrative data are prone to a certain degree of coding errors and incomplete data, which may be random or contain systemic bias.• The disease severity and depression status were not available in the database.