Role of corticosteroids in Functional Endoscopic Sinus Surgery - a systematic review and meta-analysis

Abstract

Pre-operative use of local and/or systemic corticosteroids in FESS, results in significantly reduced blood loss, shorter operative time and improved surgical field quality. Studies are limited on the intra-operative use of corticosteroids to reduce postoperative pain. Postoperative corticosteroids improve postoperative endoscopic scores in CRS and recurrence rates in cases of CRSwNP.

EUFOREA consensus on biologics for CRSwNP with or without asthma

“…5,21,22 When this is insufficient, short courses of oral corticosteroids are used (usually 30-60 mg for 14 days, sometimes reducing over time). 23,24 Sinus surgery is the treatment option for CRSwNP patients in cases failing medical treatment. [25][26][27] Recently, also more attention has been paid to the concept of "treatable traits."…”

Randomized controlled trial of steroid‐soaked absorbable calcium alginate nasal packing following endoscopic sinus surgery

“…From a medical point of view, topical (intranasal) corticosteroids have been widely used to treat CRS, both preoperatively and postoperatively, and they are known to improve both patient symptoms and recurrence rate without significant adverse effects . In particular, corticosteroids act by reducing inflammation—a major component of CRS—and suppressing the production of proinflammatory mediators, cell chemotactic factors, and adhesion molecules .…”

The use of intranasal glucocorticosteroids in the treatment of rhinosinusitis: Focus on mometasone furoate

“…инГКС хорошо изучены по всем вышеперечислен-ным показаниям в РКИ и их метаанализах [8,[41][42][43][44][45][46][47][48][49]. При остром, рецидивирующем и хроническом РС доказана эффективность применения инГКС как в виде монотера-пии, так и в качестве дополнения к антибиотикам [11,13].…”