Risk for the development of atherosclerosis in women with a high level of dental plaque and severe gingival inflammation

Söder, Birgitta; Yakob, Maha

doi:10.1111/j.1601-5037.2007.00256.x

Cited by 27 publications

(23 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A retrospective case study by Beckstrom et al 238 found a significant direct correlation between periodontal bone loss and carotid artery calcifications on panoramic radiographs. Söder et al 239 concluded in a case-control study that cIMT and intima-media area were significantly higher in women with PD than in control subjects. An earlier prospective case-control study by Söder et al 240 also found significantly higher mean values of cIMT and carotid intima-media area in patients with PD compared with control subjects.…”

Section: Association Of Periodontitis With Subclinical Carotid or Cormentioning

confidence: 99%

Periodontal Disease and Atherosclerotic Vascular Disease: Does the Evidence Support an Independent Association?

Lockhart

Bolger²,

Papapanou³

et al. 2012

Circulation

853

794

View full text Add to dashboard Cite

Abstract-A link between oral health and cardiovascular disease has been proposed for more than a century. Recently, concern about possible links between periodontal disease (PD) and atherosclerotic vascular disease (ASVD) has intensified and is driving an active field of investigation into possible association and causality. The 2 disorders share several common risk factors, including cigarette smoking, age, and diabetes mellitus. Patients and providers are increasingly presented with claims that PD treatment strategies offer ASVD protection; these claims are often endorsed by professional and industrial stakeholders. The focus of this review is to assess whether available data support an independent association between ASVD and PD and whether PD treatment might modify ASVD risks or outcomes. It also presents mechanistic details of both PD and ASVD relevant to this topic. The correlation of PD with ASVD outcomes and surrogate markers is discussed, as well as the correlation of response to PD therapy with ASVD event rates. Methodological issues that complicate studies of this association are outlined, with an emphasis on the terms and metrics that would be applicable in future studies. Observational studies to date support an association between PD and ASVD independent of known confounders. They do not, however, support a causative relationship. Although periodontal interventions result in a reduction in systemic inflammation and endothelial dysfunction in short-term studies, there is no evidence that they prevent ASVD or modify its outcomes. (Circulation. 2012;125:2520-2544.)

show abstract

Section: Association Of Periodontitis With Subclinical Carotid or Cormentioning

confidence: 99%

Periodontal Disease and Atherosclerotic Vascular Disease: Does the Evidence Support an Independent Association?

Lockhart

Bolger²,

Papapanou³

et al. 2012

Circulation

853

794

View full text Add to dashboard Cite

show abstract

“…Similarly, in a study by Söder et al, a higher IMT was characteristic of patients with an elevated bleeding index. In that study the authors observed a significantly higher IMT value in patients with gingivitis and periodontitis compared with patients without inflammation within the periodontal tissues [25]. Emingil et al also demonstrated a correlation between periodontal tissue inflammation and advanced atherosclerotic lesions of the cardiovascular system leading to acute myocardial infarction (AMI); they found a relationship between the bleeding index and a periodontal pocket depth ≥ 4 mm on the one hand and the occurrence of acute myocardial infarction on the other hand [26].…”

Section: Discussionmentioning

confidence: 81%

Prospective Analysis of the Relationship Between the State of Periodontal Tissues and Changes in Selected Cardiovascular Parameters in Patients with Type 2 Diabetes

2016

View full text Add to dashboard Cite

“…After careful selection, our review included ten studies: one longitudinal 27 , six cross-sectional 24,[74][75][76][77][78] and three casecontrol studies 73,79,80 , as shown in Table 1. Most studies were carried out in industrialized and developed countries such as the United States (USA) Sweden and other European countries.…”

Section: Resultsmentioning

confidence: 99%

Associação entre doença periodontal e aterosclerose subclínica: uma revisão sistemática

Batista

Zandonade²,

Roelke³

et al. 2011

J. vasc. bras.

View full text Add to dashboard Cite

The association between periodontal disease and the development of atherosclerosis has been studied. The systematic review of literature aims to evaluate the association between periodontal disease and subclinical atherosclerosis. A literature search of the PubMed, Scopus, LILACS, BBO, Cochrane Library and Scielo bibliographic databases was conducted using the following descriptors: "periodontal disease", "periodontitis", "carotid", and "therosclerosis". Articles were excluded if they: presented abstracts written in languages other than Portuguese, English and Spanish; experimental studies; did not contain data testing the degree of association between periodontal disease and subclinical atherosclerosis; did measure the extent of periodontal disease by parameters other than the clinical examination; did not measure the carotid artery intima-media wall thickness by ultrasonography; and covered specific population groups. The studies design, measurement protocols and reported data were compared. A total of 63 papers identified only 10 studies that met the inclusion criteria: 1 longitudinal study, 6 cross-sectional, and 3 case control studies. There was a wide heterogeneity between the studies regarding the methods of measuring periodontal disease and atherosclerosis outcomes. The conclusion is that periodontal infections are strongly associated with the development of subclinical atherosclerosis, however the mechanisms involved on the pathogenic process remain unknown.Keywords: atherosclerosis; periodontics; carotid artery diseases. ResumoA associação entre doença periodontal e o desenvolvimento de aterosclerose tem sido pesquisada. Esta revisão sistemática da literatura se propõe a verificar a associação entre a doença periodontal e a aterosclerose subclínica. A pesquisa utilizou as bases de dados: PubMed, Scopus, LILACS, BBO, Biblioteca Cochrane e Scielo com os termos: "doença periodontal", "periodontite", "carótida" e "aterosclerose". Foram excluídos artigos: que apresentaram resumos escritos em idiomas diferentes do português, inglês e espanhol; com abordagem laboratorial em modelos experimentais; sem descrição ou referência a estimadores de associação entre doença periodontal e aterosclerose subclínica; pesquisas que realizaram a medida da doença periodontal por parâmetros diferentes de exames clínicos; pesquisas que não analisaram a espessura da íntima média da artéria carótida através de exame de ultrassom; e que abordassem grupos específicos. Foram comparados os desenhos de estudo, protocolos de medida e os dados relatados. De um total de 63 referências, apenas 10 artigos contemplavam todos os critérios de inclusão, distribuídos em: 1 estudo longitudinal, 6 transversais e 3 casos controles. Observou-se uma heterogeneidade entre os estudos em relação ao método de mensuração da doença periodontal e os desfechos da aterosclerose. Concluiu-se que infecções periodontais são fortemente associadas ao desenvolvimento da aterosclerose subclínica, entretanto os mecanismos envolvidos no processo patogênico ai...

show abstract

Risk for the development of atherosclerosis in women with a high level of dental plaque and severe gingival inflammation

Abstract: The present results indicate that a high amount of dental plaque, severe gingival inflammation as well as periodontitis seem to be associated with the development of atherosclerotic lesions in women already at its early and subclinical stages.

Cited by 27 publications

References 40 publications

Periodontal Disease and Atherosclerotic Vascular Disease: Does the Evidence Support an Independent Association?

Periodontal Disease and Atherosclerotic Vascular Disease: Does the Evidence Support an Independent Association?

Prospective Analysis of the Relationship Between the State of Periodontal Tissues and Changes in Selected Cardiovascular Parameters in Patients with Type 2 Diabetes

Associação entre doença periodontal e aterosclerose subclínica: uma revisão sistemática

Contact Info

Product

Resources

About