Editorial Comment to Alcohol consumption and female urinary incontinence: A community-based study in JapanThe authors of this article conclude, "Little association is evident between alcohol consumption and urinary incontinence in middle-aged and older Japanese women. Further studies are required to confirm the role of alcohol in the prevention of this distressing condition." 1 This does not seem to be reasonable, because the results of the study show alcohol consumption indeed increases the risk of urinary incontinence (UI). In addition, there is still no available data related to the role of alcohol in the prevention of UI.Conversely, alcohol has been shown to have a direct toxic effect on peripheral nerve fibers. Zambelis et al. found that the direct toxic effect of alcohol on peripheral nerve fibers was the main etiological factor of alcoholic polyneuropathy, 2 and Ammendola et al. also showed a higher sensitivity of females towards the toxic effects of ethanol on peripheral nerve fibers. 3 Alcohol consumption has been shown to be a risk factor for the development of UI in Taiwanese women aged 20-59 years. 4 It would seem that peripheral neuropathy as a result of alcohol consumption might be a cause of the etiological association between alcohol and the onset of UI. This finding requires confirmation and the possible mechanism explaining the association requires further investigation. Nevertheless, this is the reason that it is not reasonable to state "Further studies are required to confirm the role of alcohol in the prevention of this distressing condition."UI is a complex and common condition that can be found in women of all ages. Although the etiology of UI is still controversial, many studies show that age is significantly related to the risk of UI.4-6 Furthermore, aging is a sophisticated process that is associated with different kinds of systemic diseases; for example, diabetes mellitus, hypertension, carcinoma and so on. Age is also an important risk factor of both UI and some risk factors of UI, including diabetes mellitus and hypertension. 5 Even if neuropathy as a result of alcohol consumption might be a cause of the etiological association between alcohol and the onset of UI in Taiwanese women aged 20-59 years, the study into risk factors for UI in Taiwanese women aged 60 years or over did not find that drinking alcohol had a significant association with UI. Thus, whether or not aging is the predominant factor that induces the development of UI requires further investigation. It is reasonable to explain the results by the hypothesis that age is a more important and dominant risk factor for UI than alcohol consumption.