Risk factors for low BMD in healthy men age 50 years or older: a systematic review

Παπαϊωάννου, Αλεξάνδρα; Kennedy, Courtney; Cranney, Ann; Hawker, Gillian; Brown, Jacques P.; Kaiser, Stéphanie; Leslie, William D.; O'Brien, Caitlin; Sawka, Anna M.; Khan, Aliya; Siminoski, Kerry; Tarulli, Giuseppe; Webster, Dave; McGowan, Jessie; Adachi, J.D.

doi:10.1007/s00198-008-0720-1

Cited by 123 publications

(82 citation statements)

References 53 publications

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“…The results of our study demonstrate a positive correlation between BMD at the regions of the proximal femur and weight or body mass index. Low body weight is known to be a risk factor for low BMD in the general population and several studies in CKD patients observed the same relationship [40][41][42][43] .…”

Section: Both Gender Females Malesmentioning

confidence: 67%

Evaluation of biochemical markers and bone mineral density in patients with chronic kidney disease stage 5D at the start of hemodialysis treatment

Valkovský¹,

R²,

Tvrdík³

et al. 2015

BIOMED PAP

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Background. Patients with chronic kidney disease (CKD) have significant disorders of bone and mineral metabolism. In addition, they can also develop other bone disorders including osteoporosis. This study evaluated the bone mineral density (BMD) of patients at the start of hemodialysis treatment as well as the relationship between BMD and possible risk factors or biochemical markers. Methods. The study was performed in 82 patients (28 females, 54 males). BMD was measured by dual-energy X-ray absorptiometry (DXA) at the lumbar spine and the proximal femur. Results. We found a high prevalence of 25-hydroxyvitamin D deficiency (96%; mean levels 30.0 ± 17.7 nmol/L) and a reduction of BMD in comparison with gender-and age-matched normal population values at the total hip (Z-score = -0.31 ± 1.11) and the femoral neck (Z-score = -0.48 ± 1.16), but not at the lumbar spine (Z-score = 0.68 ± 1.81). The prevalence of T-scores ≤ -2.5 SD in the group of patients over 50 years was 52.0% in females and 33.3% in males. BMD positively correlated: with male gender and calcium levels at all measured sites, with age at the lumbar spine and with weight or BMI at the proximal femur. Conclusion. CKD patients at the start of hemodialysis treatment had a high prevalence of low T-score values, corresponding to values for osteoporosis in the general population. BMD at the proximal femur was below the expected average for age and gender, but at the lumbar spine, BMD in hemodialysis patients was above average in persons without known CKD.

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Section: Both Gender Females Malesmentioning

confidence: 67%

Evaluation of biochemical markers and bone mineral density in patients with chronic kidney disease stage 5D at the start of hemodialysis treatment

Valkovský¹,

R²,

Tvrdík³

et al. 2015

BIOMED PAP

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“…For the BMI regressions we found a statistically significant interaction term for women only (p=0.007) with the estimated between-group difference of 0.46 (95% CI: 0. 13 …”

Section: Resultsmentioning

confidence: 99%

“…A meta-analysis of exercise intervention studies has shown that a range of physical activities is associated with at least some reduction in bone loss among postmenopausal women [12]. For men, a review of the literature concluded that PA has bone-positive effects, but this conclusion was largely based on smaller and less representative populations [13]. Thus, evidence is inconsistent on the relationship between PA and longitudinal BMD changes in older women and men, and studies have not included longitudinal measurements in population-based studies of men and women with additional demographic data relevant to public health stakeholders.…”

Section: Introductionmentioning

confidence: 99%

Physical activity, body mass index and bone mineral density—associations in a prospective population-based cohort of women and men: The Canadian Multicentre Osteoporosis Study (CaMos)

Langsetmo

Hitchcock

Kingwell

et al. 2012

Bone

114

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“…Male patients with osteoporosis have rarely been the focus of previous studies (Dy et al, 2011). Most studies involving males with osteoporosis have addressed prevalence, life time risk and risk factors for osteoporosis-related fractures (Papaioannou et al, 2009), or results of therapeutic interventions (Amin, 2003). Unlike previous studies, in this study we investigated the relationship between erectile dysfunction and osteoporosis in men; also we discussed the probable pathophysiology of these two diseases.…”

Section: Introductionmentioning

confidence: 91%

Possible Association between Erectile Dysfunction and Osteoporosis in Men

Dursun¹,

Özbek

Ötünçtemur

et al. 2015

Prague Med. Rep.

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Dursun M.; Özbek E.; Otunctemur A.; Cakir S. S. Report / Vol. 116 (2015) No. 1, 24) Prague Medical Key words: Erectile dysfunction -Osteoporosis -Bone mineral densityInternational Index of Erectile FunctionAbstract: Sexual dysfunction in general and erectile dysfunction (ED) in particular significantly affect men's quality of life. Some patients who have ED, also develop osteoporosis. So, in this study we investigated the relationship between erectile dysfunction and osteoporosis in men. 95 men with erectile dysfunction and 82 men with normal sexual function were included in the study. The men's sexual functions were evaluated by International Index of Erectile Function-5 items (IIEF-5). All men received a Dual Energy X-ray Absorptiometry (DEXA; Hologic) scan to measure bone mineral density (BMD) for osteoporosis. Chi-square test was used for statistical analysis. Mean age was 53.5 (38-69) in ED group and 50.1 (31-69) in control group. In ED group the men have lower T score levels than those of the control group. In conclusion, the men who have erectile dysfunction were at more risk for osteoporosis. The results of the present study demonstrate that the men with erectile dysfunction have low bone mineral density and they are at higher risk for osteoporosis. Because of easy and noninvasive evaluation of osteoporosis, patients with ED should be checked for bone mineral density and osteoporotic male subjects should be evaluated for ED.

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Risk factors for low BMD in healthy men age 50 years or older: a systematic review

Cited by 123 publications

References 53 publications

Evaluation of biochemical markers and bone mineral density in patients with chronic kidney disease stage 5D at the start of hemodialysis treatment

Evaluation of biochemical markers and bone mineral density in patients with chronic kidney disease stage 5D at the start of hemodialysis treatment

Physical activity, body mass index and bone mineral density—associations in a prospective population-based cohort of women and men: The Canadian Multicentre Osteoporosis Study (CaMos)

Possible Association between Erectile Dysfunction and Osteoporosis in Men

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