Possible Association between Erectile Dysfunction and Osteoporosis in Men

Abstract

Dursun M.; Özbek E.; Otunctemur A.; Cakir S. S. Report / Vol. 116 (2015) No. 1, 24) Prague Medical Key words: Erectile dysfunction -Osteoporosis -Bone mineral densityInternational Index of Erectile FunctionAbstract: Sexual dysfunction in general and erectile dysfunction (ED) in particular significantly affect men's quality of life. Some patients who have ED, also develop osteoporosis. So, in this study we investigated the relationship between erectile dysfunction and osteoporosis in men. 95 men with erectile dysfunction and 82 men with normal sexual function were included in the study. The men's sexual functions were evaluated by International Index of Erectile Function-5 items (IIEF-5). All men received a Dual Energy X-ray Absorptiometry (DEXA; Hologic) scan to measure bone mineral density (BMD) for osteoporosis. Chi-square test was used for statistical analysis. Mean age was 53.5 (38-69) in ED group and 50.1 (31-69) in control group. In ED group the men have lower T score levels than those of the control group. In conclusion, the men who have erectile dysfunction were at more risk for osteoporosis. The results of the present study demonstrate that the men with erectile dysfunction have low bone mineral density and they are at higher risk for osteoporosis. Because of easy and noninvasive evaluation of osteoporosis, patients with ED should be checked for bone mineral density and osteoporotic male subjects should be evaluated for ED.

Increased risk of osteoporosis in depressive patients with erectile dysfunction: A cross-sectional study from Malaysia

“…These findings confirmed our hypothesis that low BMD is associated with ED among depressive men. In part, our findings concur with the findings of two recent studies, which revealed a significant association between low BMD and ED among their participants;[ 6 17 ] however, current study differs in the nature of the sample being studied, in that we focused on depressive men.…”

“…In fact, the research aiming to explore the link between the reduced BMD and ED is in its first steps, in addition, such link is likely to be complex. Yet, previous researchers had put their efforts to suggest for the underlying mutual pathways that bring about ED and osteoporosis in men,[ 6 17 ] but not specifically in depressive men. As a result, in an attempt to elucidate the mutual etiologies and risk factors for low BMD and ED among depressive men, the postulated mediating mechanisms of the two disorders, which might in part explicate their association among this group of patients, were provided while considering the major contributing factor, i.e., depression.…”

“…Erectile dysfunction (ED) is “the inability to attain and/or maintain penile erection sufficient for satisfactory sexual intercourse.”[ 4 ] The high prevalence of ED can be read from the results of several studies that were conducted across various populations,[ 5 ] pointing it as a significant public health problem that considerably affects men's quality of life, with an estimation of more than 150 million men worldwide being affected. [ 6 ]…”

“…To the best of our knowledge, no published reports have been offered in investigating such association between bone health and erectile function among depressive men although two recent studies documented an increased risk for osteoporosis in patients with ED, but not among depressive men. [ 6 17 ] In addition, the study meant to shed light on the shared etiological pathways and risk factors for bone loss and ED that are specifically appertained to depressive men.…”

Hypogonadism and erectile dysfunction as harbingers of systemic disease

“…Recently, the relationship between osteoporosis and ED has also been questioned. Dursun et al looked at 95 men with ED and 82 men with normal erectile function ( 37 ). They found lower bone mineral density in the men with ED compared to control.…”