Risk factors for dysphagia after transoral videolaryngoscopic surgery for laryngeal and pharyngeal cancer

Tomifuji, Masayuki; Araki, Koji; Yamashita, Taku; Mizokami, Daisuke; Kamide, Daisuke; Suzuki, Hiroshi; Miyagawa, Yoshihiro; Tanaka, Shingo; Taniai, Shinichi; Shiotani, Akiko

doi:10.1002/hed.23866

Cited by 32 publications

(20 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The benefit of SNNS over ND has been reported as the low cost and low incidence of postoperative morbidities such as dysphagia, scarification, sensory dysfunction, limited motion, and pain in shoulder and upper limbs . TOS also has the advantage of preserving vocal and laryngeal functions with very low tube feeding dependency . Preservation of most of the laryngopharyngeal mucosa, nerve, and muscles related to sensory perception and swallowing reflex is the advantage of TOS.…”

Section: Discussionmentioning

confidence: 99%

Minimally invasive surgery for laryngopharyngeal cancer: Multicenter feasibility study of a combination strategy involving transoral surgery and real‐time indocyanine green fluorescence‐navigated sentinel node navigation surgery

et al. 2019

Self Cite

View full text Add to dashboard Cite

Background: Sentinel node navigation surgery using indocyanine green (ICG-SNNS) can be performed in the operation room. The combination of minimally invasive transoral surgery (TOS) with ICG-SNNS can provide functional preservation options for both primary lesions and lymph node (LN) metastasis. This multicenter feasibility study of this strategy was conducted in Japan. Methods: Patients with clinical T1 or T2, N0 oropharyngeal, hypopharyngeal, or supraglottic cancer were enrolled. The identification rate of sentinel nodes, delayed cervical LN metastasis in 2 years, and survival rate were assessed. Results: Twenty-two patients (10 oropharynx, 8 hypopharynx, 4 supraglottic cancer) were enrolled. The identification rate was 100%. One case had delayed nodal metastasis. The accuracy was 95.5%, sensitivity was 75%, and specificity was 100%. The 5-year disease-specific survival was 100%, overall survival was 72.3%, and disease-free survival was 60.5%. Conclusions: The combination of TOS with ICG-SNNS is feasible as a minimally invasive strategy and has favorable oncological outcomes. K E Y W O R D Sindocyanine green, laryngeal cancer, pharyngeal cancer, sentinel lymph node, transoral surgery A part of this research was presented at

show abstract

Section: Discussionmentioning

confidence: 99%

Minimally invasive surgery for laryngopharyngeal cancer: Multicenter feasibility study of a combination strategy involving transoral surgery and real‐time indocyanine green fluorescence‐navigated sentinel node navigation surgery

et al. 2019

Self Cite

View full text Add to dashboard Cite

show abstract

“…On the other hand, surgery is becoming more and more limited to radical surgery or early-stage endoscopic and transoral surgery. Transoral robotic surgery [ 4 ] and transoral resection [ 5 – 7 ] have recently been introduced and are gaining popularity. Transoral resection is one of the treatments of choice, but achieving good positioning can be difficult and special instruments are needed.…”

Section: Introductionmentioning

confidence: 99%

Oncological and Functional Evaluation of Open Conservation Surgery for Hypopharyngeal Cancer with/without Reconstruction

Nomura

Maki²,

Kishishita³

et al. 2018

International Journal of Otolaryngology

View full text Add to dashboard Cite

Objectives Oncological and functional results of open conservation surgery for hypopharyngeal cancer have been desired. Methods We performed a chart review of 33 patients with hypopharyngeal cancer who underwent open conservation surgery. Oncological and functional results were evaluated in surgery with primary closure (Group A) and surgery with reconstruction (Group B). Postoperative functions were evaluated by interval to resumption of oral intake, Functional Outcome Swallowing Scale (FOSS) and Communication Scale (CS). Results Five-year disease-specific and overall cumulative survival rates by Kaplan-Meier method for all cases were 95.7% and 82.3%, respectively. Duration from surgery to full oral intake was 12 days in Group A and 14 days in Group B. FOSS rates were 83.3 in Group A and 95.5 in Group B. CS was 0 in both groups. Conclusion Oncological and functional results of open conservation surgery were comparable to those with transoral surgery and chemo/radiotherapy. Our technique represents a reliable treatment for hypopharyngeal cancer.

show abstract

“…5,7,8 Furthermore, the rate of PEG dependency has been found to be low following transoral videolaryngoscopic surgery. 19 On the other hand, Rich et al conducted a multivariate analysis of prognostic factors for swallowing function in patients with advanced-stage oropharyngeal cancer who underwent transoral laser microsurgery, and found that T 4 oropharyngeal cancer (tonsil and tongue base) was associated with poor swallowing function. 20 A number of studies have reported functional outcomes such as PEG dependency and Functional Outcome Swallowing Scale scores following transoral robotic surgery performed for oropharyngeal carcinoma.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of pharyngeal swallowing pressure using high-resolution manometry during transoral surgery for oropharyngeal cancer

et al. 2021

View full text Add to dashboard Cite

Background Transoral robotic surgery is frequently described, driven by the desire to offer a less morbid alternative to chemoradiation. However, the objective evaluation of post-operative function has rarely been reported. Therefore, high-resolution manometry was used in this study to evaluate the impact of changes in peri-operative swallowing function on pharyngeal pressure events. Methods Ten patients with various stages of oropharyngeal cancer underwent transoral surgery. High-resolution manometry and videofluoroscopic swallow studies were performed before surgery and two months afterwards. The following parameters were obtained: velopharyngeal and mesopharyngeal post-deglutitive upper oesophageal sphincter pressures, velo-meso-hypopharyngeal contractile integral, upper oesophageal sphincter relaxation pressure, and pharyngeal velocity. Results There was no significant difference in pharyngeal pressure or contractile integral pre- versus post-operatively. However, pharyngeal velocity was significantly higher post-operatively than pre-operatively. Conclusion High-resolution manometry showed that transoral surgery in patients without pre-operative dysphagia preserved pharyngeal constriction. However, transoral surgery might produce scar formation in the pharynx, which could lead to narrowing of the pharynx.

show abstract

Risk factors for dysphagia after transoral videolaryngoscopic surgery for laryngeal and pharyngeal cancer

Abstract: Although the rate of PEG dependency is low in transoral surgery, surgeons should mention the risk of postoperative dysphagia when counseling patients preoperatively.

Cited by 32 publications

References 19 publications

Minimally invasive surgery for laryngopharyngeal cancer: Multicenter feasibility study of a combination strategy involving transoral surgery and real‐time indocyanine green fluorescence‐navigated sentinel node navigation surgery

Minimally invasive surgery for laryngopharyngeal cancer: Multicenter feasibility study of a combination strategy involving transoral surgery and real‐time indocyanine green fluorescence‐navigated sentinel node navigation surgery

Oncological and Functional Evaluation of Open Conservation Surgery for Hypopharyngeal Cancer with/without Reconstruction

Evaluation of pharyngeal swallowing pressure using high-resolution manometry during transoral surgery for oropharyngeal cancer

Contact Info

Product

Resources

About