2003
DOI: 10.1590/s0102-35862003000200008
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Abstract: Multidrug-resistant tuberculosis (MDR-TB) is a severe and feared problem, that is difficult to control and has shown a tendency to increase worldwide.

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Cited by 57 publications
(23 citation statements)
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References 22 publications
(23 reference statements)
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“…21 Also in another study, smoking appeared as one of the risk factors for MDR TB. 22 Smoking was found to be associated with isoniazid resistance but more evidence is needed to explain this association. 24 However, a studyconducted in Korea amongst the military worker found no significant differences in terms of smoking history (P=0.658).…”
Section: Original-articlementioning
confidence: 99%
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“…21 Also in another study, smoking appeared as one of the risk factors for MDR TB. 22 Smoking was found to be associated with isoniazid resistance but more evidence is needed to explain this association. 24 However, a studyconducted in Korea amongst the military worker found no significant differences in terms of smoking history (P=0.658).…”
Section: Original-articlementioning
confidence: 99%
“…39 In another study, alcoholism appeared as one of the risk factors for MDR TB. 22 Social stigma and lack of scientific awareness about the disease and social commitments are stated reasons for interrupting and defaulting TB treatment. In our study, association between social stigma and having MDR TB is significant with OR 2.655 (95%CI 1.071 to 5.159) (p=0.013)…”
Section: Original-articlementioning
confidence: 99%
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“…M. tuberculosis presents a significant frequency of naturally resistant mutants: 1:106 for isoniazide, 1:108 for rifampicin, but less than 1:1014 for both simultaneously. Misuse of the drugs certainly contributes to the selection of resistant strains 13,17 .…”
Section: Discussionmentioning
confidence: 99%