Rise in the number of notified human hantavirus infections since October 2011 in Baden-Württemberg, Germany

Boone, Ides; Wagner-Wiening, Christiane; Reil, Daniela; Jacob, Jens; Rosenfeld, Ulrike; Ulrich, Rainer G.; Lohr, Dorothee; Pfaff, G.

doi:10.2807/ese.17.21.20180-en

Cited by 21 publications

(1 citation statement)

References 4 publications

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“…For instance, in 2012 in Germany, reports of hantavirus infections reached an all-time high, with more than 2,800 cases [9]. The majority of these cases had been reported in the federal state of Baden-Württemberg, neighbouring Switzerland, with PUUV being the most prevalent strain [37]. Thus, although exposure to hantaviruses is currently not perceived to be a public health problem, these numbers indicate that it may be or become more frequent than suggested by the low incidence of reported cases and the low seroprevalence.…”

Section: Virus and Epidemiologymentioning

confidence: 99%

Human hantavirus infections: epidemiology, clinical features, pathogenesis and immunology

Manigold¹,

Vial²

2014

Swiss Med Wkly

104

150

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In humans, hantaviruses can cause haemorrhagic fever with renal syndrome (HFRS) or hantavirus cardiopulmonary syndrome (HCPS). Currently it is estimated that 150,000 to 200,000 cases of hantavirus disease occur each year, the majority being reported in Asia. However, human hantavirus infections are increasingly reported in the Americas and Europe. Although many of the underlying pathogenic mechanisms still remain unclear, recent evidence rather argues against a purely immune-mediated pathophysiology of human disease. Despite the high morbidity and case-fatality rates of HFRS and HCPS, respectively, no vaccine or drug is currently proven to be preventive or therapeutic. This review summarises clinical features and current epidemiological findings, as well as concepts regarding the immunology, pathogenesis and intervention strategies of human hantaviral diseases.

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Section: Virus and Epidemiologymentioning

confidence: 99%

Human hantavirus infections: epidemiology, clinical features, pathogenesis and immunology

Manigold¹,

Vial²

2014

Swiss Med Wkly

104

150

View full text Add to dashboard Cite

show abstract

Developments and Challenges in Diagnostic Virology

Barzon

Squarzon

Pacenti

et al. 2013

Viral Infections and Global Change

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Hantaviruses—Infections, Epidemiology and Hosts

Eßbauer

Krautkrämer

2014

Zoonoses - Infections Affecting Humans and Animals

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Hantaviruses are pathogens of emerging importance in different areas of the world with local outbreaks as reported in 2012 in the Yosemite national park in the US or in several endemic areas in Germany. Quite recently hantaviruses have also been detected on the African continent. The knowledge on respective small mammal hosts and virus types/subtypes has rapidly increased in the last years now including also insectivores, bats and with these several associated new viruses. Usually animals are asymptomatic reservoir carriers, although a few studies show effects on rodent populations. In humans clinical symptoms of hantavirus infections are depending on the virus type causing syndromes of different severity. However, as infections are often clinically inapparent, recorded case numbers may be underestimated. The epidemiology of hantaviruses is complex as multiple biotic and abiotic factors are involved, e.g. rodent population density, corresponding virus prevalence, mast, habitats, biodiversity, rodent ecology, or climate and local weather parameters.

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Rise in the number of notified human hantavirus infections since October 2011 in Baden-Württemberg, Germany

Abstract: Binary file ES_Abstracts_Final_ECDC.txt matches

Cited by 21 publications

References 4 publications

Human hantavirus infections: epidemiology, clinical features, pathogenesis and immunology

Human hantavirus infections: epidemiology, clinical features, pathogenesis and immunology

Developments and Challenges in Diagnostic Virology

Hantaviruses—Infections, Epidemiology and Hosts

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