Rheumatoid Arthritis and Cardiovascular Risk: Perspectives of Treatment With Statins

Anichkov, D. A.; Шостак, Н. А.

doi:10.20996/1819-6446-2005-1-3-47-53

Racionalʹnaâ farmakoterapiâ v kardiologii

2005

DOI: 10.20996/1819-6446-2005-1-3-47-53

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Rheumatoid Arthritis and Cardiovascular Risk: Perspectives of Treatment With Statins

D. A. Anichkov

Н. А. Шостак

Abstract: Ревматоидный артрит и сердечно-сосудистый риск: перспективы применения статинов Д.А. Аничков, Н.А. Шостак Кафедра факультетской терапии им. акад. А.И. Нестерова Российского государственного медицинского университета, Москва В обзоре рассмотрены сердечно-сосудистые факторы риска у больных ревматоидным артритом (РА). Представлены перспективы применения статинов при РА. Суммированы данные клинических исследований влияния статинов на воспалительную активность заболевания и функцию эндотелия у больных РА.

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Cited by 2 publications

References 46 publications

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Cardiovascular risk in patients with inflammatory arthritis

Anichkov,

Shostak,

Timofeev

2024

Klinicist

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Rheumatoid and other inflammatory arthritis (ankylosing spondylitis and psoriatic arthritis) have a high risk of cardiovascular disease (CVD). It is caused by the accelerated development of atherosclerosis associated with a chronic systemic inflammatory process. Nevertheless, traditional CVD risk factors (hypertension, smoking, dyslipidemia) are also important for patients with inflammatory arthritis. The greatest amount of data has been accumulated regarding the relationship between CVD and rheumatoid arthritis. Due to the difficulties in diagnosing coronary heart disease and other CVD, it is of great importance to identify patients at high and very high risk. The use of scales for assessing the total cardiovascular risk SCORE/SCORE 2 with a coefficient of 1.5 allows to identify patients who need measures to reduce their high risk of CVD. Control of the of the disease activity, lifestyle modification, therapy with statins and antihypertensive drugs in accordance with current guidelines, caution when prescribing non-steroidal anti-inflammatory drugs and minimizing the dose of glucocorticoids are the main components of the strategy for reducing the risk of CVD in patients with inflammatory arthritis.

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Cardiovascular risk in patients with inflammatory arthritis

Anichkov,

Shostak,

Timofeev

2024

Klinicist

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Analytical Assessment of Out-Patient Treatment of Patients With Rheumatoid Arthritis

Бакалец

Никифорова

2016

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Objective: to carry out the analytical assessment of outpatient management of patients with rheumatoid arthritis in real clinical practice and study the structure of comorbid pathology. Material and methods. The medical records of 88 patients have been analyzed at 6 outpatient clinics of Gomel. The Charlson comorbidity index was applied for the quantitative assessment of the comorbid status. Results. The most common provoking factors of the development of rheumatoid arthritis were acute respiratory viral infections and exacerbation of chronic diseases; and the background disease was thyroid pathology. The most frequent complications of rheumatoid arthritis were osteoarthritis, anemia of chronic inflammation, osteoporosis, coronary heart disease. Comorbid pathology occured in 97.7 % of the patients with rheumatoid arthritis. Conclusion. At present, the problems of management of patients with rheumatoid arthritis are late diagnostics; discrepancy of real treatment to the modern recommendations of EULAR; insufficient use of disease-modifying antirheumatic drugs; absence of individual approach aimed at early detection of comorbid pathology and its adequate treatment.

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Rheumatoid Arthritis and Cardiovascular Risk: Perspectives of Treatment With Statins

Cited by 2 publications

References 46 publications

Cardiovascular risk in patients with inflammatory arthritis

Cardiovascular risk in patients with inflammatory arthritis

Analytical Assessment of Out-Patient Treatment of Patients With Rheumatoid Arthritis

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