Revisiting the Fetal Loss Rate After Second-Trimester Genetic Amniocentesis

Odibo, Anthony O.; Gray, Diane L.; Dicke, Jeffrey M.; Stamilio, David M.; Macones, George A.; Crane, James P.

doi:10.1097/aog.0b013e318162eb53

Cited by 158 publications

(109 citation statements)

References 16 publications

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“…Odibo et al [10] published in 2008 their experience with higher risk in cases of fetuses with structural abnormalities. We acknowledge their fi ndings because, in our series, all seven fetuses/children with poor outcome also had a pathological karyotype or malformations.…”

Section: Discussionmentioning

confidence: 99%

“…Odibo et al [10] , in the same study in which they examined the total fetal loss rate after amniocentesis (0.4 % ; 0.97 % , < 24 weeks), compared the rate in the group without this procedure (0.26 % ; 0.84 % , < 24 weeks).…”

Section: Discussionmentioning

confidence: 99%

“…In addition, procedure-related complications after amniocentesis performed with needles of different diameters were explored [1, 5,6,8,17] . Moreover, an eventually elevated risk of fetal loss was examined in association with transplacental needle insertion [3,4] , angle of puncture [5,7] , numerous punctures [9] , fetal abnormalities [10] , and experience and specialization of the operator (obstetrician-gynecologist or perinatologist) [2,12] .…”

Section: Introductionmentioning

confidence: 99%

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Three years’ experience of using a 29-gauge atraumatic needle for amniocentesis

Tchirikov

Arnold²,

Oshovskyy³

et al. 2012

Journal of Perinatal Medicine

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Aims: To quantify the procedure-related complication rate after using modifi ed technique of amniocentesis with a 29-gauge (29-G) pencil-point needle.Methods: This is a prospective, descriptive study of 316 amniocenteses that were performed by means of atraumatic 29-G pencil-point needle under ultrasound control. Results: A total of 316 amniocenteses were observed through the postprocedural period. The median time needed to retrieve 15 mL of amniotic fl uid was 4 min. A total of 19 pregnancies were terminated after genetic testing. No case was regarded as procedure-related fetal loss. No other complications were observed. Seventeen children were born before 37 completed weeks of gestation and fi ve children had a birth weight < 2000 g. Conclusions:Amniocentesis with the 29-G atraumatic pencil-point needle seems to be a safe procedure with extremely low risk of complications and is a good alternative to the traditional 22-G Quincke needle.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Three years’ experience of using a 29-gauge atraumatic needle for amniocentesis

Tchirikov

Arnold²,

Oshovskyy³

et al. 2012

Journal of Perinatal Medicine

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show abstract

“…This meant that prenatal screening for NTD could be extended with the screening for DS. This way, women of advanced maternal age could now be offered a screening test before opting for an invasive amniocentesis that bears a certain risk of miscarriage (Eddleman et al, 2006, Odibo et al, 2008. The discovery of AFP as a second trimester screening marker for DS triggered researchers to look for other potential screening markers to even further improve the prenatal detection by screening.…”

Section: Prenatal Screening For Down Syndromementioning

confidence: 99%

Innovations in Down Syndrome Screening

Koster¹,

Vries²,

Visser³

et al. 2011

Prenatal Diagnosis and Screening for Down Syndrome

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“…25,26 In our department, we have preformed a retrospective controlled study in order to estimate the fetal loss rate after second trimester amniocentesis.…”

Section: 10 Fetal Lossmentioning

confidence: 99%