Review: A Recent Review in Applications of Heterocyclic Compounds as Antimicrobial Agent

Abstract

A wide development in the field of multidrug resistance in antimicrobial activity which enhance the search for development of new medicinal drugs with high potential. Schiff base heterocyclic metal complex with imine moiety, act as important antimicrobial agents due to their versatile properties such as chelation, adaptability of fine structure for a specific biological action, and chemotheraptic drugs. Schiff base compounds derived from various heterocyclic platforms have been competently reviewed.

Significant Aspects of Heterocyclic Schiff Bases and Their Metal Complexes

“…The discussion pertaining to this chapter will purely be focused on the HSBs and related metal complexes containing at least one heterocyclic unit on either side of the imine group. Quite a few structural representations of HSBs (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15) and some of their complexes (16)(17)(18)(19)(20)(21)(22)(23)(24) are shown in Figure 3.…”

“…The phenomenal pharmacological properties of HSBs have encouraged Schiff base complexation to a different level. HSB complexes have striking biological activities that include anticancer, antibacterial, antifungal, antimalarial, anti-inflammatory, antiproliferative, and antipyretic [7]. In addition, there are so many HSB complexes that exhibit excellent catalytic activity due to their exceptional stabilities.…”