Reversible Layer‐by‐Layer Deposition on Solid Substrates Inspired by Mussel Byssus Cuticle

Abstract

The protective coating on mussel (Mytilus galloprovincialis) byssus has attracted considerable research interest because of its excellent mechanical properties such as hardness and extensibility. These special properties are known to be highly related with specific interactions between mussel foot protein-1 and metal ions. In particular, the complexation between catechols in mfp-1 and iron(III) has been identified as a key interaction. This finding has given opportunities for pursuing promising applications. Herein, we report that emulating the properties of the mussel byssus cuticle provides an important platform for developing reversible layer-by-layer (LbL) deposition, an advanced technique for surface modification. LbL films were constructed on solid substrates by sequential immersion of substrates into solutions containing iron(III) and catecholic compounds. The thickness of the LbL films was effectively controlled by increasing the immersion steps, and the reversibility of the LbL deposition was demonstrated by addition of a chelating agent.

Mussel‐Inspired Approach to Constructing Robust Multilayered Alginate Films for Antibacterial Applications

“…The resultant substrate was immersed in an acidic Fe 3+ solution (pH 2.0) followed by phosphate buffered saline (PBS; pH 7.4) ( Figure ). A solid substrate was pretreated with pDA to introduce catechol groups, and Alg‐C spin coating was carried out, yielding a multilayered Alg‐C film on the pDA‐coated surface. The substrate was then treated with a FeCl 3 solution to generate catechol–Fe 3+ coordination bonds between the pDA‐coated surface and Alg‐C or between Alg‐C molecules.…”

Phenolic film engineering for template-mediated microcapsule preparation

“…TA has a high spectrum of bioactivities such as antioxidant, 37 antibacterial, 38 anticarcinogenic, 39 antimutagenic 40 and antiviral 41 properties. Through electrostatic or hydrogen bonding interactions, TA has been assembled via the LbL assembly method with poly(dimethyldiallylamide), 42 poly(allylamine), [42][43][44] poly(Nvinylcaprolactam), 45,46 poly(N-vinylpyrrolidone), [45][46][47] poly(ethylene oxide), 45 poly(N-isopropylacrylamide), 45,46 poly(2-n-propyl-2-oxazoline), 48 Fe III ions 49,50 and proteins 51 to form thin films. The first microcapsules based on TA were prepared by Shutava et al 42 via multistep LbL assembly in 2005.…”

Phenolische Bausteine für die Assemblierung von Funktionsmaterialien

“…In jüngster Zeit wurde der mehrschichtige Aufbau von Phenolen auch mit Metallionen anstelle von Polymeren durchgeführt . Diese Schichten werden in einem mehrstufigen LbL‐Prozess aufgebaut und haben andere physikalisch‐chemische Eigenschaften als MPN‐Filme, die aus den gleichen Komponenten (d. h. TA und Fe III ) hergestellt wurden, z.…”

“…B. eine unterschiedliche Abbaukinetik und Permeabilität . Da Metallionen und phenolische Substrate in einem breiten Spektrum von Lösungsmitteln löslich sind, kann der mehrschichtige Aufbau sowohl in organischen als auch in wässrigen Lösungsmitteln durchgeführt werden . Die Schichtordnung, d. h. ob TA oder Fe III zuerst abgeschieden wird, hat einen wesentlichen Einfluss auf die endgültigen Filmeigenschaften, ebenso wie die Nachbehandlung bei verschiedenen pH‐Werten .…”