Phenolische Bausteine für die Assemblierung von Funktionsmaterialien

Rahim, Md. Arifur; Kristufek, Samantha L.; Pan, Shuaijun; Richardson, Joseph J.; Caruso, Frank

doi:10.1002/ange.201807804

Cited by 36 publications

(5 citation statements)

References 250 publications

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“…We employed tannic acid as the interparticle ligand and added it sequentially to the MOF NP/RBC mixed solution after a short incubation time (≈30 s). Tannic acid is frequently used as an organic building block [17] in MOFs, due to its well-known biodegradability and strongmultivalent coordination to various metal ions. Coupled with the additional strong metal-phenolic interactions, the colloidal MOF NP-based exoskeleton in armored RBCs can be created rapidly, in seconds.…”

Section: Resultsmentioning

confidence: 99%

Modular Assembly of Red Blood Cell Superstructures from Metal–Organic Framework Nanoparticle‐Based Building Blocks

Guo

Wang

et al. 2020

Adv Funct Materials

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Bio/artificial hybrid nanosystems based on biological matter and synthetic nanoparticles (NPs) remain a holy grail of materials science. Herein, inspired by the well‐defined metal–organic framework (MOF) with diverse chemical diversities, the concept of “armored red blood cells” (armored RBCs) is introduced, which are native RBCs assembled within and protected by a functional exoskeleton of interlinked MOF NPs. Exoskeletons are generated within seconds through MOF NP interlocking based on metal‐phenolic coordination and RBC membrane/NP complexation via hydrogen‐bonding interactions at the cellular interface. Armored RBC formation is shown to be generalizable to many classes of MOF NPs or any NPs that can be coated by MOF. Moreover, it is found that armored RBCs preserve the original properties of RBCs (such as oxygen carrier capability and good ex ovo/in vivo circulation property) and show enhanced resistance against external stressors (like osmotic pressure, detergent, toxic NPs, and freezing conditions). By modifying the physicochemical properties of MOF NPs, armored RBCs provide the capability for blood nitric oxide sensing or multimodal imaging. The synthesis of armored RBCs is straightforward, reliable, and reversible and hence, represent a new class of hybrid biomaterials with a broad range of functionalities.

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Section: Resultsmentioning

confidence: 99%

Modular Assembly of Red Blood Cell Superstructures from Metal–Organic Framework Nanoparticle‐Based Building Blocks

Guo

Wang

et al. 2020

Adv Funct Materials

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“…This class of molecules finds many applications in the field of organic synthesis, 1 pharmaceuticals, 2 and material science. 3 Resveratrol is a stilbenoid type of natural phenol found in grapes, blueberries, and peanuts and is widely used as a dietary supplement (Figure 1 ). 4 Caffeic acid is found in plants and is an essential intermediate in the biosynthesis of lignin (Figure 1 ).…”

Section: Table 1 Solvent Optimization Of the Reaction C...mentioning

confidence: 99%

Anthraquinone-Catalyzed Photooxidation of Boronic Acids in a Bio-Based Solvent (2-Me-THF)

Gkizis

Serviou

Balaskas

et al. 2023

Synlett

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The phenol moiety appears in a wide variety of natural products, exhibiting biological activity, and in numerous active pharmaceutical compounds. Boronic acids are potential precursors of the phenol scaffold and a plethora of efforts has been focused in developing novel and green protocols, targeting their chemoselective transformation into phenols. Photochemistry is a rapidly expanding research field converting light energy into chemical potential. Photochemical aerobic processes possess additional advantages to photochemistry and may find applications in chemical industries. Herein, a low-catalyst loading anthraquinone-catalyzed photochemical process is demonstrated, under CFL lamp irradiation, while exploiting 2-Me-THF as the reaction medium for the conversion of boronic acids to phenols. Furthermore, a broad substrate scope was employed.

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“…Polyphenols are naturally occurring secondary metabolites found widely in plants and they serve diverse roles within different plant species. 37,38 Their unique physicochemical properties, such as pH-responsiveness and metal chelation, have garnered signicant attention in materials science. 39,40 Additionally, their promising biological activity further contributes to their growing importance and potential in various applications.…”

Section: Introductionmentioning

confidence: 99%