Retrograde transsynaptic cellular degeneration in mammillary and ventral tegmental nuclei following limbic decortication in rabbits of various ages

Bleier, Ruth

doi:10.1016/0006-8993(69)90162-0

Cited by 83 publications

(25 citation statements)

References 20 publications

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“…Me of the rodents used to be regarded as the subdivision of the medial mammillary nucleus which did not project to the anterior thalamic nuclei, but to the tegmentum Powell and Cowan, 1954;Bleier, 1969], The present observations show that Me projects to the medial portion of AM (or probably the nu cleus commissuralis interanteromedialis).…”

Section: Discussionmentioning

confidence: 54%

“…Yamadori [1973] showed that Ml sends fibers to AV and probably to AM. In the cat [Niimi et al, 1972] and rabbit [Bleier, 1969], the homologous subdivision to Ml of the rat projects to AV and AD. And some investigators Powell and Cowan, 1954] showed that the Ml of the rat, or the basal subdivi sion of the rabbit, projects to AD.…”

Section: Discussionmentioning

confidence: 99%

“…Mm is known to project ipsilaterally to AM Powell and Cowan, 1954;Bleier, 1969). Yamadori [1973] showed in the rat that Mm projects to AM and AV.…”

Section: Discussionmentioning

confidence: 99%

“…It is generally accepted that the mammillothalamic tract arises from the mammillary body and that the tract goes into the anterior thalamic nuclei [Gurdjian, 1927;Yamagata, 1927;Rioch, 1931;Le Gros Clark, 1932;Le Gros Clark and Meyer, 1950;Krieg, 1932Krieg, , 1947Papez, 1932;Papez and Aronson, 1934;Cowan and Powell, 1954;Powell and Cowan, 1954;Guillery, 1957;Fry et al" 1963;Zyo et al" 1963;Bleier, 1969;Fry, 1970;Fry and Cowan, 1972;Niimi et ai., 1972;Yamadori, 1973;Hopkins and Dekker, 1975;LaVail, 1975;Dekker and Kuypers, 1976;Van derKooye tal., 1979).…”

Section: Introductionmentioning

confidence: 99%

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A horseradish peroxidase study on the mammillothalamic tract in the rat

Watanabe

Kawana²

1980

Cells Tissues Organs

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The mammillary projections to the anterior thalamic nuclei were investigated in the rat, using the horseradish peroxidase (HRP) method. Pars centralis of the medial mammillary nucleus projects to the medial portion of the anteromedial nucleus (AM). Pars medialis (Mm) of the medial mammillary nucleus sends fibers to the ipsilateral AM and sparsely to the medial portion of the contralateral side. The ventral and dorsal portions of Mm project to the anterior and posterior portions of AM, respectively. The pars lateralis (Ml) and pars posterior (Mp) of the medial mammillary nucleus send fibers predominantly to the ipsilateral anteroventral nucleus and sparsely to the contralateral side. A slight difference between Ml and Mp projections was observed. The lateral mammillary nucleus projects bilaterally to the anterodorsal nucleus.

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Section: Discussionmentioning

confidence: 54%

Section: Discussionmentioning

confidence: 99%

“…Mm is known to project ipsilaterally to AM Powell and Cowan, 1954;Bleier, 1969). Yamadori [1973] showed in the rat that Mm projects to AM and AV.…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

A horseradish peroxidase study on the mammillothalamic tract in the rat

Watanabe

Kawana²

1980

Cells Tissues Organs

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“…1,2 As pathology in a particular brain region may induce both structural and functional abnormalities in its fields of projection, 3 thalamic pathology might be expected to accompany disorders, including SZ, that involve cortical anomalies. Structural and functional abnormalities have previously been described in multiple cortical regions in SZ, in particular, the prefrontal cortex.…”

Section: Introductionmentioning

confidence: 99%

Thalamic transcriptome screening in three psychiatric states

2009

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The prefrontal cortex has been implicated in schizophrenia (SZ) and affective disorders by gene expression studies. Owing to reciprocal connectivity, the thalamic nuclei and their cortical fields act as functional units. Altered thalamic gene expression would be expected to occur in association with cortical dysfunction. We screened the expression of the entire human genome of neurons harvested by laser-capture microdissection (LCM) from the thalamic primary relay to dorsolateral prefrontal cortex in three psychiatric disease states as compared with controls. Microarray analysis of gene expression showed the largest number of dysregulated genes was in SZ, followed by major depression (MD) and bipolar mood bipolar (BP) (1152, 385 and 288, respectively). Significantly, IGF1-mTOR-, AKT-, RAS-, VEGF-, Wnt-and immune-related signaling, eIF2-and proteasome-related genes were unique to SZ. Vitamin D receptor and calcium signaling pathway were unique to BP. AKAP95 pathway and pantothenate and CoA biosynthesis were unique to MD. There are significant differences among the three psychiatric disorders in MDNp cells. These findings offer new insights into the transcriptional dysregulation in the thalamus of SZ/BP/MD subjects.

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Mesolimbocortical Dementia

Torack¹

1986

Arch Neurol

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Retrograde transsynaptic cellular degeneration in mammillary and ventral tegmental nuclei following limbic decortication in rabbits of various ages

Cited by 83 publications

References 20 publications

A horseradish peroxidase study on the mammillothalamic tract in the rat

A horseradish peroxidase study on the mammillothalamic tract in the rat

Thalamic transcriptome screening in three psychiatric states

Mesolimbocortical Dementia

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