“…According to Dennis and Norris (2015), the proinflammatory cytokines and eicosanoids play a key role in the inflammatory process caused by SARS-CoV-2, in the same way as TNF-α, IL-6, IL-12, IL-17, IL-1β, and IFN- (Chousterman et al, 2017). Meanwhile, IL-10 limits the expansion of tissue lesions in experimental models (Savarin & Bergmann, 2018;Ashrafizadeh et al, 2020). Considering as described by Huang et al (2005), high levels of monokine were detected in the serum of patients with SARS in the acute phase, and these monokines are induced by IL-6, IL-8, IL-18, interferon-γ-inducible protein-10 (CXCL10 or IP-10), monocyte chemoattractant protein-1 (MCP-1), IFN-γ, and TGF-β (Huang et al, 2005;Savarin & Bergmann, 2018).…”