Results of heparin-bonded ePTFE-covered stents for chronic occlusive superficial femoral artery disease

Abstract

Heparin-bonded covered stents seem to provide a valid alternative to surgical treatment of long occlusive lesions in the SFA. Randomized trials and long-term data are required before considering the technique as a new standard of care.

Three-year outcome of the heparin-bonded Viabahn for superficial femoral artery occlusive disease

“…8 Patients of this cohort may also have been included in other subanalyses. 3,[9][10][11][12] Data were retrospectively collected and anonymously analyzed. Retrospective research of patients' charts is not in the scope of the Dutch Law on research with human participants, and therefore neither formal approval of the Central Committee on Research Involving Human Subjects nor patient consent was required.…”

“…The treatment protocol has been described before. 3 In summary, the common femoral artery was approached either percutaneously or by surgical cutdown. In case of a concomitant lesion in the common or deep femoral artery, an endarterectomy was performed.…”

“…Initial 1-year results of three case series and one randomized trial have demonstrated a primary patency rate of 67% to 78%. [3][4][5][6] The randomized VIASTAR trial (Viabahn endoprosthesis with Propaten bioactive surface vs bare nitinol stent in the treatment of long lesions in SFA occlusive disease) comparing the heparin-bonded Viabahn with baremetal stents proved the superiority of the Viabahn over bare-metal stents at 24 months. 7 There was, however, no significant impact on clinical outcome and target revascularization rate.…”

Immobilization of Actively Thromboresistant Assemblies on Sterile Blood‐Contacting Surfaces

“…[16] Preliminary analysis of heparin-bonded ePTFE covered stents in the superficial femoral artery suggests a similar effect. [17, 18] Attenuation of thrombin production at the blood-contacting interface, therefore, may be a critical step in the design of blood-compatible materials that improve the clinical performance of blood-contacting implants.…”

First Application of an Absorbable Skin Stapler in Peripheral Vascular Surgical Procedures

“…It enhances convalescence in peripheral arterial disease. Favorable outcomes are seen with a lower number of SSI's [9]. However, there still is a necessity for open surgery in selected cases.…”