Response to: ‘Painful knee but not hand osteoarthritis is an independent predictor of mortality over 23 years follow-up of a population-based cohort of middle-aged women’ by Gao et al

Abstract

Response to: 'Painful knee but not hand osteoarthritis is an independent predictor of mortality over 23 years follow-up of a population-based cohort of middle-aged women' by Gao et alWe thank Gao et al 1 for their interest in our paper. 2Gao et al highlighted a number of issues related to discordance between pain and radiographic changes and sensitivity of the pain assessment. Although a single definition of knee osteoarthritis (KOA) remains elusive, the presence of knee pain is the main symptom of KOA 3-5 and there is still a strong relationship between pain and radiographic knee osteoarthritis (ROA).

Modern achievements in pharmacotherapy of osteoarthritis based on endo- and phenotyping

“…У пациенток с ОА с болью и признаками ОА в коленном суставе отметили увеличение риска в 2 раза по всем причинам смертности и в 4 раза по смертности от сердечно-сосудистых заболеваний. Боль в коленных суставах сопровождалась более высокими показателями смертности (скорректированное отношение рисков составило 1,5 по всем причинам и 3 для сердечно-сосудистых заболеваний) [33].…”