Response of yellow catfish (Pelteobagrus fulvidraco) to different dietary concentrations of aflatoxin B1 and evaluation of an aflatoxin binder in offsetting its negative effects

Abstract

Response of yellow catfish (Pelteobagrus fulvidraco) to different dietary concentrations of aflatoxin B1 and evaluation of an aflatoxin binder in offsetting its negative effectsRespuesta del bagre amarillo (Pelteobagrus fulvidraco) a diferentes concentraciones dietéticas de aflatoxina B1 y la evaluación de una bentonita para contrarrestar sus efectos negativos ABSTRACT. Aflatoxin B1 (AFB1), produced by Aspergillus flavus and Aspergillus parasiticus, is one of the major mycotoxins to affect animal health. AFB1 contamination of aquafeed is widespread, especially in countries with humid, tropical climates. The most applied method for protecting animals against aflatoxicosis is the use of clay minerals. Growth performance, immunosuppressive effects (bactericidal activity, lysozyme activity, albumin/globulin ratio, alternative complement pathway activity, and protein content), and pathology parameters were used to evaluate the response of yellow catfish (Pelteobagrus fulvidraco) to increasing concentrations of AFB1 and test the protective effect of dietary supplementation with a bentonite (dioctahedral montmorillonite) based AFB1 binder. Triplicate groups of yellow catfish with an average weight of 2.0 ± 0.1 g were fed diets containing 0, 200, 500, and 1,000 g/kg of AFB1 alone, or diets containing 0, 200, 500, and 1,000 g/kg of AFB1 along with 2 g/kg AFB1 binder, for 12 weeks. Results showed that diets containing increasing amounts of AFB1 had a significantly lower (P = 0.002) survival rate. There was a statistical significant reduction in weight gain, final body weight, and specific growth rate, and an increase in feed conversion ratio (FCR) influenced by the levels of AFB1 in the diet (P < 0.001 for all parameters), as well as increasing protection due to the presence of the binder (P = 0.046, P = 0.014, P = 0.038, and P = 0.485, respectively). The immunosuppressive nature of AFB1 in yellow catfish diets was confirmed through observation of lower bactericidal activity (P = 0.001), lower lysozyme activity (P = 0.006), reduced total protein (P = 0.002), and enhanced albumin/globulin ratio (P = 0.004). Fish fed diets contaminated with AFB1 and supplemented with the AFB1 binder showed better improvement in FCR (P = 0.019). These results indicate that AFB1 has a negative impact on yellow catfish growth and survival rate. The AFB1 binder protected fish from the toxic effects of AFB1. RESUMEN.La aflatoxina B1 (AFB1), producida por Aspergillus flavus y Aspergillus parasiticus, es una de las principales micotoxinas que afectan la salud animal. La contaminación de alimentos acuícolas con AFB1 es común, especialmente en países con climas húmedos y tropicales. El método más usado para proteger a los animales contra la aflatoxicosis es el uso de arcillas. Para evaluar la respuesta del bagre amarillo (Pelteobagrus fulvidraco) a concentraciones crecientes de AFB1 y evaluar el efecto protector de una bentonita (montmorillonita dioctaédrica), se analizaron el crecimiento, efectos inmunosupresores (actividad bactericida, relación a...

Ot Sazanı (Ctenopharyngodon idella)’nda Aflatoksin B1’in Genotoksik ve Toksikopatolojik Etkileri

“…Sepahdari et al [24] investigated that there was a decrease in weight gain and SGR in fish treated with 75 ppb and 100 ppb AFB 1 per Kg of diet as compared to control group after two months. The similar results were observed by Wang et al [25] in Yellow catfish (Pelteobagrus fulvidraco) fed with 200, 500 and 1.000 μg kg -1 of AFB 1 in feed which showed decrease weight gain and growth rate and altered feed conversion ratio.…”

“…The intestine showed hypoplasia of goblet cells, sloughing of epithelial cells and leukocytic infiltration. Histopathological studies revealed liver cell degeneration and necrosis and progressive fat deposition at a level of 75 ppb and 100 ppb AFB 1 /kg of diets after 2 months [25] . The results are also in agreement with the study of [22] , who reported that AFB 1 in Catla catla KHAN, KHAN, SADIQUE, AHMAD, HASSAN AHMAD, AHAD, SHAH, AHMAD, SHAH, REHMAN fish causing histopathological changes in liver, kidneys and intestine.…”

Assessment of the Presence of Total Aflatoxins and Aflatoxin B1 in Fish Farmed in Two Cameroonian Localities

“…Tilapia was the less contaminated fish species while catfish was the most contaminated one ( Table 1 ). According to cited reports [ 24 ], catfish (40.40 ppb) was also more contaminated than tilapia (15.11 ppb). This difference in the contamination could be explained by the variability of metabolic activities from one species to another.…”

Ефективність Використання Мінералів Природного Походження В Раціоні Самиць Коропа

“…Учені рекомендують застосовувати бентоніти та сапоніти в харчовій промисловості, тваринництві, сільському господарстві, медицині як ефективні сорбційні матеріали, антиоксиданти та високодисперсні мінерали, оскільки вони мають специфічну каркасну будову молекулярних сит і містять у своєму складі безліч мікро-та макроелементів [10,11]. Оскільки ці мінерали активно застосовуються в рибництві, що доведено позитивними результатами у годівлі різних видів риб, доцільним було б застосувати їх у раціонах самок коропа, оскільки репродуктивна здатність риб значною мірою залежить від забезпечення організму мікроелементами, котрі є активними центрами антиоксидантного захисту і входять до складу біологічно активних складових, що регулюють обмін речовин [1,2,[12][13][14][15][16][17].…”