Response of pups with maternal derived antibody to modified-live canine parvovirus vaccine

Buonavoglia, Canio; Tollis, Maria; Buonavoglia, Domenico; Puccini, Alberto

doi:10.1016/0147-9571(92)90007-e

Cited by 24 publications

(19 citation statements)

References 2 publications

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“…1,7 Attempts to develop immunization strategies to overcome this problem have to date been based on administration of multiple vaccinations from about 6 weeks of age until about 16-18 weeks of age.…”

Section: Introductionmentioning

confidence: 99%

mentioning

confidence: 99%

“…1 Interference by maternal antibodies is regarded as a major cause of canine parvovirus (CPV) vaccination failure in young dogs. 1,7 Attempts to develop immunization strategies to overcome this problem have to date been based on administration of multiple vaccinations from about 6 weeks of age until about 16-18 weeks of age. 2 In this study, we tested an immunoblot clinic-based enzyme-linked immunosorbent assay (ELISA) method to semiquantitatively assay CPV antibodies in sera of pregnant bitches and their offspring to study the kinetics of maternal antibodies in pups and the response of pups to vaccination.…”

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confidence: 99%

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Assessment of Maternal Antibody Decay and Response to Canine Parvovirus Vaccination Using a Clinic-Based Enzyme-Linked Immunosorbent Assay

et al. 1996

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Abstract.Interference caused by maternal antibodies is considered a major cause of canine parvovirus (CPV) vaccination failure. In this study, an immunoblot clinic-based enzyme-linked immunosorbent assay (ELISA) method was used to detect CPV antibodies in sera of pregnant bitches and their offspring to study the response of pups to vaccination. With a easily accessible procedure for CPV antibody determination, the veterinarian should be able to gauge the response of pups after vaccination. The validity of the technique was tested in parallel against the standard hemagglutination inhibition (HI) test. Results of the ELISA were correlated with those of the standard HI method for quantification of CPV antibodies. With the ELISA, successfully immunized pups were identified, allowing for a more reliable and cost-effective program of vaccination. This simple clinicbased test could be used for the assessment of vaccination status of pups during the critical phase of 6 to about 16 weeks of age. This study is the first in which vaccination response to CPV in pups was followed, using a clinic-based ELISA for CPV antibody monitoring.Maternal antibody transfer in the dog occurs primarily by intestinal absorption from the colostrum during the initial 2 days of the pup's life.1 Interference by maternal antibodies is regarded as a major cause of canine parvovirus (CPV) vaccination failure in young dogs. 1,7 Attempts to develop immunization strategies to overcome this problem have to date been based on administration of multiple vaccinations from about 6 weeks of age until about 16-18 weeks of age. 2In this study, we tested an immunoblot clinic-based enzyme-linked immunosorbent assay (ELISA) method to semiquantitatively assay CPV antibodies in sera of pregnant bitches and their offspring to study the kinetics of maternal antibodies in pups and the response of pups to vaccination. With an easily accessible inclinic procedure for CPV antibody determination, it should be possible to monitor response of pups after vaccination with CPV. The validity of the technique was tested in parallel with the standard hemagglutination inhibition (HI) test. Materials and methodsAnimals. Ten pure-bred, pregnant beagle dogs a were used in this study. The bitches were allowed to whelp normally, and 4 pups were selected at random from each litter for antibody studies.

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Section: Introductionmentioning

confidence: 99%

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Assessment of Maternal Antibody Decay and Response to Canine Parvovirus Vaccination Using a Clinic-Based Enzyme-Linked Immunosorbent Assay

et al. 1996

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“…Interference by maternally derived antibodies is regarded as a major cause of Canine Parvovirus and Canine distemper virus vaccination failures in young dogs (Baker et al, 1959;Pollock and CarMichael, 1982;Buonavoglia et al, 1992). Veterinarians and researchers have come to the conclusion that the surest way to know that a puppy has adequately responded to vaccination or to confirm the immune status in a mature dog is to check the antibody levels in the dog's blood or serum.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of post-vaccination immunity to canine distemper and parvoviruses in Benin City, Nigeria

Eghafona¹,

N²,

Jacob³

et al. 2007

Afr. J. Biotechnol.

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A study was conducted to determine the immune status of dogs vaccinated against Canine Parvovirus (CPV) and Canine Distemper Virus (CDV) by a clinic-based immunoblot enzyme-linked immunosorbent assay (ELISA) using a commercially available 120 sample immunocomb® test kit for canine parvo and distemper IgG in Benin City, Nigeria. Out of 120 dogs sampled, 63 (52.5%) were females while 57 (47.5%) were males. 84 (70%) dogs were exotic breeds while 36 (30%) were mongrels. Majority of the dogs (35, 29.17%) were less than one year old and the age range of all dogs sampled was between 9 weeks and 10 years. Analysis of data showed that there was no significant difference (P < 0.05) between sex, breed, age and level of immunity. A non-parametric chi-square contingency analysis of antigens (CPV and CDV) and level of immunity revealed that there was a high significant association (p < 0.001) between CPV and CDV antigens and level of immunity of the vaccinated dogs sampled.

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“…In the current case, it is possible that interference caused by these antibodies led to vaccination failure. 4,21 However, it seems that the presence of parvovirus may not be related to the clinical manifestation of the disease as it relates to the 10 other puppies.…”

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An Outbreak of Canine Coronavirus in Puppies in a Greek Kennel

et al. 2010

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Abstract. Canine coronavirus (CCoV) is usually the cause of mild gastroenteritis in dogs and is known to have spread worldwide. However, to date, no CCoV cases have been confirmed in Greece. In the present work, the authors investigated an outbreak of enteritis in puppies from a Greek kennel for the presence of CCoV. Dogs were presented with clinical signs of diarrhea, anorexia, weakness, depression, dehydration, and 1 death. Canine coronavirus type II was detected by reverse transcription nested polymerase chain reaction in all 11 puppies, whereas 1 puppy presented dual infection with CCoV type II and canine parvovirus 2. Surprisingly, sequence analysis of the samples revealed higher similarity to the pantropic CCoV II strain CB/05 than to other reference strains, in the most variable region of the S gene.

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Response of pups with maternal derived antibody to modified-live canine parvovirus vaccine

Cited by 24 publications

References 2 publications

Assessment of Maternal Antibody Decay and Response to Canine Parvovirus Vaccination Using a Clinic-Based Enzyme-Linked Immunosorbent Assay

Assessment of Maternal Antibody Decay and Response to Canine Parvovirus Vaccination Using a Clinic-Based Enzyme-Linked Immunosorbent Assay

Evaluation of post-vaccination immunity to canine distemper and parvoviruses in Benin City, Nigeria

An Outbreak of Canine Coronavirus in Puppies in a Greek Kennel

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