Respiratory symptoms and lung function of aluminum potroom workers.

Kongerud, Johny; Grønnesby, Jon Ketil; Magnus, Per

doi:10.5271/sjweh.1785

Cited by 59 publications

(47 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We have previously shown that these exposures increase bronchial responsiveness7, and the incidence of respiratory symptoms, 8 and that the prevalence of airways obstruction increases with the duration of exposure in the potrooms. 9 An increased mortality due to COPD in aluminium potroom workers has recently been reported by R0nneberg. "0 The relation between occupational exposures and the development of airway obstruction is, however, lacking."…”

mentioning

confidence: 98%

Relation between decline in FEV1 and exposure to dust and tobacco smoke in aluminium potroom workers.

Søyseth

Kongerud

1997

Occup Environ Med

View full text Add to dashboard Cite

Objectives-To investigate the relation between pulmonary function and occupational exposure in aluminium pot operators. Methods-2795observations were obtained in 630 workers over six years of follow up. An autoregressive method of analysis was used.Results-After adjustment for FEV, in the three previous years, the effect of smoking v no smoking on FEV, was -43-1 ml, 95% confidence interval (95% CI) -72X3 to -13-9. Similarly, an increase in the exposure to particulates by 1 mg/m3 corresponded to a decrease in FEV, of -11 9 ml, 95% CI -19 9 to -39. Age was a significant predictor of both FEV, and FVC. Conclusion-Exposure to particulates in aluminium potrooms seems to increase the decline in FEV,, thereby increasing the risk of development of chronic obstructive lung disease in pot operators.

show abstract

mentioning

confidence: 98%

Relation between decline in FEV1 and exposure to dust and tobacco smoke in aluminium potroom workers.

Søyseth

Kongerud

1997

Occup Environ Med

View full text Add to dashboard Cite

show abstract

“…For each patient, information was collected about tobacco smoking, presumed diagnosis at the time of request for analysis of the samples, and job history, including dates of beginning and end of each occupation. 4. A 26 year-old man, who had a 6 month history of working in the aluminium smelting industry as a crushed bath operator, was investigated for dyspnoea at work.…”

Section: Patientsmentioning

confidence: 99%

“…Evidence concerning a relationship between work in the aluminium industry and lung disease has been documented by several studies [1][2][3][4]. Respiratory investigations have concentrated on four diseases: asthma syndrome, chronic obstructive lung disease, lung cancer and pulmonary fibrosis [5].…”

mentioning

confidence: 99%

Mineralogical analysis of the respiratory tract in aluminium oxide-exposed workers

Voisin¹,

Fişekçi²,

Buclez³

et al. 1996

Eur Respir J

View full text Add to dashboard Cite

M Mi in ne er ra al lo og gi ic ca al l a an na al ly ys si is s o of f t th he e r re es sp pi ir ra at to or ry y t tr ra ac ct t i in n a al lu um mi in ni iu um m o ox xi id de e--e ex xp po os se ed d w wo or rk ke er rs s ABSTRACT: A retrospective study was conducted in order to characterize the retention of fibrous and nonfibrous mineral particles in the respiratory tract in subjects with previous occupational exposure in the aluminium industry. Bronchoalveolar lavage (BAL) fluid (three samples) or lung parenchyma (two samples) were studied using analytical transmission electron microscopy in five patients.A high concentration of aluminium fibres (>10 7 fibres·g -1 dry lung) was identified in two lung tissue samples, and aluminium fibres were also identified in BAL fluid in three patients. All fibres were short (mean length: 1-2 µm), with no fibre longer than 5 µm. Some biopersistence of these fibres in the respiratory tract is suggested from these observations, since fibres were identified in biological samples collected more than 4 yrs after cessation of exposure in four out of five patients.Occupational physicians should be aware of possible exposure to short, thin aluminium fibres during primary aluminium production. Further studies are needed to assess the potential health effects of these fibres. Industrial hygiene measurements should also be performed to document the potential sources of exposure to aluminium fibres in this industry.

show abstract

“…Exposure to respiratory irritants or mineral particles in the workplace has been reported as a possible risk factor of bronchial hyperresponsiveness (BHR) [1][2][3][4]. A decline in respiratory function has been observed among subjects with BHR, suggesting that the latter might be a predisposing factor of bronchopulmonary obstructive disease [5,6].…”

mentioning

confidence: 99%

Measurement of bronchial responsiveness by forced oscillation technique in occupational epidemiology

Iwatsubo²,

Hubert³

et al. 1994

Eur Respir J

View full text Add to dashboard Cite

M Me ea as su ur re em me en nt t o of f b br ro on nc ch hi ia al l r re es sp po on ns si iv ve en ne es ss s b by y f fo or rc ce ed d o os sc ci il ll la at ti io on n t te ec ch hn ni iq qu ue e i in n o oc cc cu up pa at ti io on na al l e ep pi id de em mi io ol lo og gy y Changes in resistance (∆R 0 %), frequency dependence of resistance (∆P) and resonant frequency (∆F%) determined by the FOT were compared to the ∆FEV 1 %. Receiver operating characteristic (ROC) curves were established to determine values of the changes in FOT parameters which corresponded to the best sensitivity and specificity for classifying the subjects as hyperresponsive or nonresponsive on the methacholine challenge test.Significant correlations were observed between ∆FEV 1 % and ∆R 0 %, ∆P and ∆F% respectively. The ROC curves showed the following cut-off values of FOT parameters to be the best values for classifying the subjects according to the presence or absence of 20% fall in FEV 1 : a 65% increase in R 0 (sensitivity 75%; specificity: 76%); a decrease of 65×10 -3 hPa·l -1 ·s 2 in P (sensitivity 58%; specificity 83%); a 50% increase in F (sensitivity 75%; specificity 62%).Our results suggest that the FOT is a useful test for assessment of bronchial hyperresponsiveness when compared to spirometry, and can be applied to epidemiological studies of a bronchial challenge test in normal active working populations.

show abstract

Respiratory symptoms and lung function of aluminum potroom workers.

Cited by 59 publications

References 12 publications

Relation between decline in FEV1 and exposure to dust and tobacco smoke in aluminium potroom workers.

Relation between decline in FEV1 and exposure to dust and tobacco smoke in aluminium potroom workers.

Mineralogical analysis of the respiratory tract in aluminium oxide-exposed workers

Measurement of bronchial responsiveness by forced oscillation technique in occupational epidemiology

Contact Info

Product

Resources

About