Research progress of functional lactic acid bacteria

Liu, Xuejun; Wang, Mengmeng; Zhu, Chang; Gou, Meng-Xing; Yan, Xiaohui

doi:10.2991/iceesd-17.2017.116

Cited by 4 publications

(4 citation statements)

References 10 publications

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“…In previous studies, the antifungal substances of LAB can secrete and produce are mainly organic acids, fatty acids, bacteriocins, hydrogen peroxide, carbon dioxide, cyclic dipeptide, and other antibacterial substances during the growth process, which can inhibit the growth of pathogenic Escherichia coli , Staphylococcus aureus , Streptococcus suis , etc., this feature promotes the intestinal health of humans and animals ( Jang et al, 2016 ; Wang et al, 2020 ; Li and Gong, 2022 ). As shown in Table 1 , W. cibaria BYL4.2 has inhibitory effects on E. coli , S. aureus , Pseudomonas aeruginosa , and Listeria monocytogenes , and the inhibition zones are 25.33 ± 0.58, 22.67 ± 1.15, 18.00 ± 0.00, and 17.67 ± 0.58, respectively.…”

Section: Resultsmentioning

confidence: 99%

Impact of Weissella cibaria BYL4.2 and its supernatants on Penicillium chrysogenum metabolism

Yao

Wang

et al. 2022

Front. Microbiol.

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Lactic acid bacteria (LAB) can produce a vast spectrum of antifungal metabolites to inhibit fungal growth. The purpose of this study was to elucidate the antifungal effect of isolated Weissella cibaria BYL4.2 on Penicillium chrysogenum, the antifungal activity of W. cibaria BYL4.2 against P. chrysogenum was evaluated by the superposition method, results showed that it had obviously antifungal activity against P. chrysogenum. Studying the probiotic properties of BYL4.2 and determining it as beneficial bacteria. Furtherly, different treatments were carried out to characterize the antifungal activity of cell-free supernatant (CFS) produced by W. cibaria BYL4.2, and it was shown that the CFS was pH-dependent, partly heat-sensitive, and was not influenced by proteinaceous treatment. The CFS of W. cibaria BYL4.2 was analyzed by high-performance liquid chromatography (HPLC) and found the highest content of lactic acid. Screening of metabolic markers by a non-targeted metabolomics approach based liquid chromatography-mass spectrometry (LC-MS). The results speculated that organic acid especially detected D-tartaric acid was the main antifungal substance of CFS, which could cause the down-regulation of metabolites in the ABC transporters pathway, thereby inhibiting the growth of P. chrysogenum. Therefore, this study may provide important information for the inhibitory mechanism of W. cibaria BYL4.2 on P. chrysogenum, and provide a basis for further research on the antifungal effect of Weissella.

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Section: Resultsmentioning

confidence: 99%

Impact of Weissella cibaria BYL4.2 and its supernatants on Penicillium chrysogenum metabolism

Yao

Wang

et al. 2022

Front. Microbiol.

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“…Probiotics can improve and regulate intestinal health, effectively relieve intestinal discomfort such as constipation, diarrhea, inflammatory gastrointestinal diseases, irritable bowel syndrome, and FD, and protect intestinal health to the greatest extent [ 57 , 58 , 59 ]. Through their colonization of the intestinal mucosa and interactions with the mucus layer, probiotics regulate the immune response, thus enhancing the ability to ward off external threats [ 60 ]. Following their establishment in the intestinal tract, the bioactive compounds responsible for their beneficial effects can help to maintain the equilibrium of the gut microbiota; this includes boosting the population of beneficial bacteria in the intestinal ecosystem while decreasing the abundance of harmful bacteria, ultimately bolstering intestinal immunity [ 61 ].…”

Section: Relationship Between Probiotics and Intestinal Floramentioning

confidence: 99%

Research Progress for Probiotics Regulating Intestinal Flora to Improve Functional Dyspepsia: A Review

Shen,

Xie,

et al. 2024

Foods

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Functional dyspepsia (FD) is a common functional gastrointestinal disorder. The pathophysiology remains poorly understood; however, alterations in the small intestinal microbiome have been observed. Current treatments for FD with drugs are limited, and there are certain safety problems. A class of active probiotic bacteria can control gastrointestinal homeostasis, nutritional digestion and absorption, and the energy balance when taken in certain dosages. Probiotics play many roles in maintaining intestinal microecological balance, improving the intestinal barrier function, and regulating the immune response. The presence and composition of intestinal microorganisms play a vital role in the onset and progression of FD and serve as a critical factor for both regulation and potential intervention regarding the management of this condition. Thus, there are potential advantages to alleviating FD by regulating the intestinal flora using probiotics, targeting intestinal microorganisms. This review summarizes the research progress of probiotics regarding improving FD by regulating intestinal flora and provides a reference basis for probiotics to improve FD.

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“…Bioactive peptides can act as immune modulators ( Qian et al, 2011 ), and are antihypertensive by inhibiting angiotensin-converting enzyme (ACE) ( Phelan et al, 2014 ), as in yogurts ( Papadimitriou et al, 2007 ) and antioxidants as in sourdough ( Coda et al, 2012 ) and yogurt ( Sabeena Farvin et al, 2010 ). Antioxidant peptides have been found in soybean milk fermented by LAB and these can effectively eliminate free radicals ( Liu et al, 2017 ). Antioxidant properties may also be the consequence of EPS production ( Rahbar Saadat et al, 2019 ).…”

Section: Lab Co-cultures To Multiply Functionalitiesmentioning

confidence: 99%

Understanding the Mechanisms of Positive Microbial Interactions That Benefit Lactic Acid Bacteria Co-cultures

et al. 2020

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Microorganisms grow in concert, both in natural communities and in artificial or synthetic co-cultures. Positive interactions between associated microbes are paramount to achieve improved substrate conversion and process performance in biotransformation and fermented food production. The mechanisms underlying such positive interactions have been the focus of numerous studies in recent decades and are now starting to be well characterized. Lactic acid bacteria (LAB) contribute to the final organoleptic, nutritional, and health properties of fermented food products. However, interactions in LAB co-cultures have been little studied, apart from the well-characterized LAB co-culture used for yogurt manufacture. LAB are, however, multifunctional microorganisms that display considerable potential to create positive interactions between them. This review describes why LAB co-cultures are of such interest, particularly in foods, and how their extensive nutritional requirements can be used to favor positive interactions. In that respect, our review highlights the benefits of co-cultures in different areas of application, details the mechanisms underlying positive interactions and aims to show how mechanisms based on nutritional interactions can be exploited to create efficient LAB co-cultures.

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Research progress of functional lactic acid bacteria

Cited by 4 publications

References 10 publications

Impact of Weissella cibaria BYL4.2 and its supernatants on Penicillium chrysogenum metabolism

Impact of Weissella cibaria BYL4.2 and its supernatants on Penicillium chrysogenum metabolism

Research Progress for Probiotics Regulating Intestinal Flora to Improve Functional Dyspepsia: A Review

Understanding the Mechanisms of Positive Microbial Interactions That Benefit Lactic Acid Bacteria Co-cultures

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