“…H6ppener, Institute of Molecular Biology, State University of Utrecht, Padualaan 8, 3584 CH Utrecht, The Netherlands [3,4]. In medullary thyroid carcinoma (MTC; a tumour of the CT-producing thyroidal C-cells), both CT mRNA and CGRP mRNA are produced from the human CT/CGRP gene (or 'CALC-I gene', [5]). In addition, a structurally related gene has been identified in the human genome, encoding a second CGRP (CGRP-II) differing from the previously known human CGRP (CGRP-I) in 3 of the 37 amino acids.…”