Report of a clinical case of dog infected by Hepatozoon canis in Southern Brazil

Imidocarb Use in Animals

“…Monocytosis, loss of appetite, vomiting, stagnation and polydipsia were observed in a dog infected with Hepatozoon canis, imidocarb (6 mg/kg, SC) was administered 3 times with one week intervals, and the agent was not observed in the blood 2 weeks later (Lilliehöök et al, 2019). In addition, case reports indicate that imidocarb (4 mg/kg, IM, 3 months with a 15-day interval), prednisolone (1 mg/kg, PO, twice a day-BID, 4 weeks), vitamins and fluid therapy (Marchetti et al, 2009) or imidocarb (5 mg/kg, SC) and doxycycline (5 mg/kg, PO, BID, 15 days) administration reported to be effective (Da Silva et al, 2011). When imidocarb (5-6 mg/kg, SC, 6 times at intervals of 1 week) and toltrazuril + emodepside treatments are compared in dogs naturally infected with Hepatozoon canis, both applications are not sufficient in the treatment (De Tommasi et al, 2014).…”

Aspectos anatomopatológicos em cães naturalmente infectados por Hepatozoon canis

“…No Brasil, há diversos estudos sobre a prevalência do parasito (O'Dwyer et al 2006, Mundim et al 2008b, Spolidorio et al 2009, Gomes et al 2010, que em algumas regiões foi considerado endêmico (Paludo et al 2003) e relatos sobre as manifestações clínicas e hematológicas em animais parasitados (Gondim et al 1998, Paludo et al 2003, Melo Júnior et al 2008, Mundim et al 2008a, Gomes et al 2010, Silva et al 2011. No entanto, são escassas as descrições patológicas, com apenas um estudo sobre as alterações histopatológi-cas em músculos esqueléticos obtidos através de biópsia de três cães parasitados por Hepatozoon sp.…”