Report of 12 cases with tracheobronchial mucormycosis and a review

Abstract

Tracheobronchial mucormycosis is a rare but severe disease with high mortality because of its nonspecific clinical presentations and variable predisposing factors.

Mucormycosis: an unusual masquerader of an endobronchial tumour

“…Pulmonary mucormycosis presenting as an endobronchial lesion is rare. A recent analysis revealed that only 60 cases of mucormycosis involving larger airways have been reported in the literature so far . Diabetic patients (85%) have a higher tendency to develop major airway lesions compared to others .…”

“…Steroid therapy (20%) and renal insufficiency (18.3%) comes next in the order. Primary bronchus is the most frequently involved location . Most often they present as a solitary mass or infiltrates radiologically.…”

“…Most often they present as a solitary mass or infiltrates radiologically. Only 23.2% of the patients are reported to have radiological abnormality suggestive of an endobronchial lesion such as bronchial mass . They mimic a malignant lesion bronchoscopically.…”

“…Bronchoscopic findings are commonly described as an obstructed airway (95%) with a grey‐white mucoid material with surrounding mucosal oedema and necrosis . Hyperaemic mucosa can appear in diabetic patients . The recovery of Zygomycetes can be difficult in culture.…”

“…Pulmonary lesions mostly tend to present as consolidation or cavitation. Pulmonary mucormycosis presenting as an endobronchial tumour is rare and only a few cases have been reported . They are more commonly seen in patients with poorly controlled diabetes 85% .…”