Repair of Cranial Bone Defects in Children Using Synthetic Hydroxyapatite Cranioplasty (CustomBone)

Beuriat, Pierre-Aurélien; Lohkamp, Laura-Nanna; Szathmari, A.; Rousselle, Christophe; Sabatier, Isabelle; Rocco, Federico Di; Mottolèse, C.

doi:10.1016/j.wneu.2019.05.052

Cited by 13 publications

(8 citation statements)

References 26 publications

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“…These include bioactive glass, 44,50–52,195 β‐TCP, 11 HAp obtained from natural sources like eggshells 83 and xenografts, 235 as well as synthetic HAp. The commercially available Bio‐Oss®, which is derived from bovine HAp and synthetic HAp such as OsteoGraf® 35 and CustomBone®, 85 have all produced successful clinical outcomes in human studies. The high biocompatibility and bone regeneration exhibited by these materials make them suitable replacements for autografts and allografts.…”

Section: Discussionmentioning

confidence: 99%

“…In a human study, pure synthetic carbonate HAp called Bongros® chips showed similar healing levels as autografts 84 . CustomBone® is a synthetic HAp bone substitute used to replace autologous bone in craniotomy procedures of pediatric patients exhibiting effective clinical outcomes 85 . Synthetic carbonated HAp has been compared to Bio‐Oss® in a randomized controlled clinical trial.…”

Section: Classificationmentioning

confidence: 99%

“…84 CustomBone ® is a synthetic HAp bone substitute used to replace autologous bone in craniotomy procedures of pediatric patients exhibiting effective clinical outcomes. 85 Synthetic carbonated HAp has been compared to Bio-Oss ® in a randomized controlled clinical trial. The results showed that synthetic HAp degraded more rapidly than Bio-Oss ® and promoted new bone formation in dental sockets following tooth extraction.…”

Section: Ceramicsmentioning

confidence: 99%

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A novel classification of bone graft materials

2022

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Over the past few decades, the field of biomaterials concerning bone tissue engineering has gained a significant amount of interest. This has led to new biomaterials to be used as bone substitute materials. Despite the rapid increase in the types and forms of bone substitutes, a comprehensive classification encompassing all types of bone graft materials that have so far been developed and evaluated is lacking. Therefore, this review aims to integrate and bring together the published data on bone substitutes within the last 5 years and produce a novel classification that would provide bone material researchers with a better understanding of what materials have so far been used and evaluated and the areas, where research is lacking and deserves more attention. The literature available in all major databases was obtained and filtered using an elimination criterion to extract all the articles related to studies that tested bone substitute materials in nonclinical and clinical trials over the last 5 years. The review article would provide bone material researchers with an insight into the materials that have been evaluated for bone tissue engineering applications and identify future perspectives for bone graft material research.

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Section: Discussionmentioning

confidence: 99%

Section: Classificationmentioning

confidence: 99%

Section: Ceramicsmentioning

confidence: 99%

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A novel classification of bone graft materials

2022

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“…Severe bone defects may lead to disability, affect the individual’s ability to live and work, and cause serious social and economic burdens. Bone defect repair is one of the most common regenerative surgeries, with more than 200,000 bone transplants performed worldwide every year ( Beuriat et al, 2019 ).…”

Section: Introductionmentioning

confidence: 99%

Advances in Copper-Based Biomaterials With Antibacterial and Osteogenic Properties for Bone Tissue Engineering

Shen

Kong

et al. 2022

Front. Bioeng. Biotechnol.

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Treating bone defects coupled with pathogen infections poses a formidable challenge to clinical medicine. Thus, there is an urgent need to develop orthopedic implants that provide excellent antibacterial and osteogenic properties. Of the various types, copper-based biomaterials capable of both regenerating bone and fighting infections are an effective therapeutic strategy for bone tissue engineering and therefore have attracted significant research interest. This review examines the advantages of copper-based biomaterials for biological functions and introduces these materials’ antibacterial mechanisms. We summarize current knowledge about the application of copper-based biomaterials with antimicrobial and osteogenic properties in the prevention and treatment of bone infection and discuss their potential uses in the field of orthopedics. By examining both broad and in-depth research, this review functions as a practical guide to developing copper-based biomaterials and offers directions for possible future work.

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“…There are a number of successful Ca-P ceramic scaffolds or fillers already available on the market used in cancellous bone replacement in non load-bearing indications (JectOS/ARE-X®BONE, CustomBone®, CronOS®, Engipore®). Unfortunately clinical solutions for cortical bone regeneration remain extremely limited [9,[18][19][20][21][22].…”

Section: Introductionmentioning

confidence: 99%

Bone-like ceramic scaffolds designed with bioinspired porosity induce a different stem cell response

Panseri

Montesi

Hautcoeur

et al. 2021

J Mater Sci: Mater Med

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Biomaterial science increasingly seeks more biomimetic scaffolds that functionally augment the native bone tissue. In this paper, a new concept of a structural scaffold design is presented where the physiological multi-scale architecture is fully incorporated in a single-scaffold solution. Hydroxyapatite (HA) and β-tricalcium phosphate (β-TCP) bioceramic scaffolds with different bioinspired porosity, mimicking the spongy and cortical bone tissue, were studied. In vitro experiments, looking at the mesenchymal stem cells behaviour, were conducted in a perfusion bioreactor that mimics the physiological conditions in terms of interstitial fluid flow and associated induced shear stress. All the biomaterials enhanced cell adhesion and cell viability. Cortical bone scaffolds, with an aligned architecture, induced an overexpression of several late stage genes involved in the process of osteogenic differentiation compared to the spongy bone scaffolds. This study reveals the exciting prospect of bioinspired porous designed ceramic scaffolds that combines both cortical and cancellous bone in a single ceramic bone graft. It is prospected that dual core shell scaffold could significantly modulate osteogenic processes, once implanted in patients, rapidly forming mature bone tissue at the tissue interface, followed by subsequent bone maturation in the inner spongy structure.

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Repair of Cranial Bone Defects in Children Using Synthetic Hydroxyapatite Cranioplasty (CustomBone)

Cited by 13 publications

References 26 publications

A novel classification of bone graft materials

A novel classification of bone graft materials

Advances in Copper-Based Biomaterials With Antibacterial and Osteogenic Properties for Bone Tissue Engineering

Bone-like ceramic scaffolds designed with bioinspired porosity induce a different stem cell response

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