Repair of Bile Duct Injuries With Gore-Tex Vascular Grafts

Novel reconstruction of the extrahepatic biliary tree with a biosynthetic absorbable graft

“…A review of the literature shows that a small number of institutions are conducting novel research in an effort to redefine the manner in which this complication is addressed. Several groups have utilized their experience with vascular repair and transitioned that knowledge to the reconstruction of CBD injuries 4,5,13–16 . Many of these studies were complicated by low patency rates and short lengths of follow‐up 4,7,13 .…”

Bile Duct Regeneration with an Artificial Bile Duct Made of Gelatin Hydrogel Nonwoven Fabrics

“…In previous studies, various materials have been used for ABD including autologous tissue such as blood vessels and ureters 4,5 , non-degradable materials such as polytetrafluoroethylene 8 , degradable materials such as polylactic acid and collagen 6,7 , and bioengineered materials. 13 Non-degradable materials have achieved limited success because they remain as foreign substances in the bile duct.…”

“…3 Autologous tissue, 4,5 non-degradable materials, and degradable materials have been used as ABD materials. [6][7][8] However, an ABD has not been successfully put into clinical use yet. This is in contrast to the fact that artificial blood vessels have been in practical use for decades and are indispensable for cardiovascular surgery.…”

Surgical therapies for iatrogenic bile duct lesions (IBDL) – review

“…Another experimental study, performed on dogs, used thin-walled FEP-ringed Gore-Tex vascular grafts, found to be useful in the repair of IBDLs, especially in complete transections of the CBD. The ductility and flexibility of the material allows any type of anastomosis to be performed, especially when bile duct-gut anastomosis is technically difficult (28).…”