Bile Duct Regeneration with an Artificial Bile Duct Made of Gelatin Hydrogel Nonwoven Fabrics

Uemoto, Yusuke; Taura, Kojiro; Nakamura, Daichi; Xuefeng, Li; Nam, Nguyen Hai; Kimura, Yusuke; Yoshino, Kenji; Fuji, Hiroaki; Nishio, Toshikazu; Yamamoto, Gen; Koyama, Yukinori; Seo, Satoru; Tsuruyama, Tatsuaki; Iwaisako, Keiko; Uemoto, Shinji; Tabata, Yasuhiko; Hatano, Etsuro

doi:10.1089/ten.tea.2021.0209

Cited by 2 publications

(2 citation statements)

References 29 publications

(38 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Another area of tissue engineering development is tissue engineering of bile ducts using hydrogels as the scaffold [ 16 ].…”

Section: Scaffolds In Tissue Engineering—recent Findings and Current ...mentioning

confidence: 99%

Biomimetic Scaffolds—A Novel Approach to Three Dimensional Cell Culture Techniques for Potential Implementation in Tissue Engineering

Górnicki,

Lambrinow,

Golkar-Narenji

et al. 2024

Nanomaterials

View full text Add to dashboard Cite

Biomimetic scaffolds imitate native tissue and can take a multidimensional form. They are biocompatible and can influence cellular metabolism, making them attractive bioengineering platforms. The use of biomimetic scaffolds adds complexity to traditional cell cultivation methods. The most commonly used technique involves cultivating cells on a flat surface in a two-dimensional format due to its simplicity. A three-dimensional (3D) format can provide a microenvironment for surrounding cells. There are two main techniques for obtaining 3D structures based on the presence of scaffolding. Scaffold-free techniques consist of spheroid technologies. Meanwhile, scaffold techniques contain organoids and all constructs that use various types of scaffolds, ranging from decellularized extracellular matrix (dECM) through hydrogels that are one of the most extensively studied forms of potential scaffolds for 3D culture up to 4D bioprinted biomaterials. 3D bioprinting is one of the most important techniques used to create biomimetic scaffolds. The versatility of this technique allows the use of many different types of inks, mainly hydrogels, as well as cells and inorganic substances. Increasing amounts of data provide evidence of vast potential of biomimetic scaffolds usage in tissue engineering and personalized medicine, with the main area of potential application being the regeneration of skin and musculoskeletal systems. Recent papers also indicate increasing amounts of in vivo tests of products based on biomimetic scaffolds, which further strengthen the importance of this branch of tissue engineering and emphasize the need for extensive research to provide safe for humansbiomimetic tissues and organs. In this review article, we provide a review of the recent advancements in the field of biomimetic scaffolds preceded by an overview of cell culture technologies that led to the development of biomimetic scaffold techniques as the most complex type of cell culture.

show abstract

“…Another area of tissue engineering development is tissue engineering of bile ducts using hydrogels as the scaffold [ 16 ].…”

Section: Scaffolds In Tissue Engineering—recent Findings and Current ...mentioning

confidence: 99%

Biomimetic Scaffolds—A Novel Approach to Three Dimensional Cell Culture Techniques for Potential Implementation in Tissue Engineering

Górnicki,

Lambrinow,

Golkar-Narenji

et al. 2024

Nanomaterials

View full text Add to dashboard Cite

show abstract

“…L929 cells originating from mouse fibroblasts have been widely used in biomedical research for biocompatibility evaluation due to their ability to grow rapidly and maintain stable characteristics. 51,52 The adhesion and proliferation of L929 cells on the PE1 ABD artificial bile duct demonstrated favorable biocompatibility, indicating that the PE1 composite used in its fabrication is nontoxic to L929 cells. These results support the suitability of the PE1 ABD for subsequent in vivo experiments.…”

Section: Biocompatibility Of Pe1 Abdmentioning

confidence: 99%

Fabrication of 3D printed PCL/PEG artificial bile ducts as supportive scaffolds to promote regeneration of extrahepatic bile ducts in a canine biliary defect model

Cai,

Nan,

Tang

et al. 2023

J. Mater. Chem. B

View full text Add to dashboard Cite

show abstract

Bile Duct Regeneration with an Artificial Bile Duct Made of Gelatin Hydrogel Nonwoven Fabrics

Cited by 2 publications

References 29 publications

Biomimetic Scaffolds—A Novel Approach to Three Dimensional Cell Culture Techniques for Potential Implementation in Tissue Engineering

Biomimetic Scaffolds—A Novel Approach to Three Dimensional Cell Culture Techniques for Potential Implementation in Tissue Engineering

Fabrication of 3D printed PCL/PEG artificial bile ducts as supportive scaffolds to promote regeneration of extrahepatic bile ducts in a canine biliary defect model

Contact Info

Product

Resources

About