Remineralization of Artificial Caries-Like Lesions in vivo by a Self-Administered Mouthrinse or Paste

Abstract

A mouthrinse formulated to fulfill physicochemical requirements for rapid remineralization of early carious lesions was investigated in vivo using intraoral appliances in adults. Human enamel slabs with artificially induced early lesions were embedded in the appliances. Complete rehardening of the inner 40–50 μm and twofold rehardening of the remaining body of the lesion occurred in 160-μm deep lesions with a 1-min mouthrinse on each of 14 consecutive days. Saliva alone rehardened the inner 20 μm only. At least the inner half of lesions 65 μm deep rehardened completely and the remaining body of the lesion rehardened fourfold over 14 days. Monofluorophosphate toothpastes, tested similarly remineralized to the same extent as saliva alone and increased the surface layer hardness. The remineralizing solution shows potential value as a daily mouthrinse for the prevention or reversal of early carious lesions.

Effect of Delaying Toothbrushing During Bleaching on Enamel Surface Roughness: An In Vitro Study

“…12,13 When fluoride is used, formation of calcium fluoride prevents enamel surface demineralization. 12,35,36 Because the toothbrushing regimen was the same in all the groups in the present study, improvements in enamel surface roughness cannot be attributed to the role of fluoride in the toothpaste.…”

Hydrogen Peroxide Tooth Whitening Agent Effect on the Nanomechanical Properties of Enamel

“…Microhardness changes have been related to a loss (demineralisation) or gain (remineralisation) of the mineral/organic content of the dental structure, the direction of hydroxyapatite crystals and the anisotropic nature of enamel [23,24,6]. The nanoindentation microhardness test is suitable for determining small changes in surface microhardness and elastic modulus of dental hard tissue [25].…”

In Vitro Evaluation of the Effect of Delaying Toothbrushing With Toothpaste on Enamel Microhardness Subsequent to Bleaching the Teeth With 15% Carbamide Peroxide

“…9,20 On the other hand, the fluoride ion can prevent demineralization and microhardness decrease by forming a layer of calcium fluoride on the enamel surface. 9,21,22 Apart from the effect of fluoridated toothpaste, artificial saliva was used in the present study as an environment to store the specimens. Saliva can have a role in remineralization and can change the oral cavity conditions after bleaching in favor of the improvements in tooth structure properties.…”